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Asthma clinical trials

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NCT ID: NCT00424125 Completed - Asthma Clinical Trials

Involving Community Pharmacies in Improving Asthma Outcomes in an Urban Pediatric Population

Start date: July 2006
Phase: N/A
Study type: Interventional

This study seeks to determine whether education provided in community pharmacies and monthly reminder calls can improve compliance with asthma medications. We hypothesize that those pediatric patients with asthma 12 months to 12 years of age who receive comprehensive asthma care as part of a validated intervention (1) who are randomized to receive enhanced community pharmacy care will have significantly greater compliance with inhaled corticosteroids (ICS) six months after enrollment when compared with patients receiving usual pharmacy care. As secondary outcomes, we further hypothesize that they will have less unscheduled healthcare utilization and improved functional outcomes and QOL. (1) Teach SJ, Crain EF, Quint DM, Hylan ML, Joseph JG. Improved Asthma Outcomes in a High Morbidity Pediatric Population: Results of an Emergency Department-based Randomized Clinical Trial. Archives of Pediatric and Adolescent Medicine. 2006;160:535-541.

NCT ID: NCT00424008 Completed - Asthma Clinical Trials

Study of Inhaled Glucocorticosteroids/Long-Acting Bronchodilator Drugs in Subjects With Asthma That Have Been Taking Inhaled Glucocorticosteroids (Study P04705AM1)

Start date: April 2007
Phase: Phase 3
Study type: Interventional

This study is being conducted to demonstrate the non-inferiority between two inhaled glucocorticosteroids and long-acting bronchodilator combination drugs called mometasone furoate/formoterol fumarate in a metered-dose inhaler (MDI) and fluticasone propionate/salmeterol in a dry powder inhaler (DPI) on lung function. Information on the onset of action, the overall safety, and how the drugs control asthma will also be assessed. The study is approximately 1 year in duration.

NCT ID: NCT00422747 Completed - Asthma Clinical Trials

Early Diagnosis of Asthma in Young Children

Start date: April 2007
Phase: N/A
Study type: Interventional

The overall aim of the study is an early asthma diagnosis in young children by the use of non-invasive biomarkers of airway inflammation /oxidative stress in exhaled air, and early lung function measurements

NCT ID: NCT00422305 Completed - Asthma Clinical Trials

Assessment of Lung Structure and Function of Infants Born Prematurely

Start date: January 2007
Phase:
Study type: Observational

The purpose of this study is to evaluate the growth of the lung and how easily gas can be taken up by the lung in healthy infants born at full term without any breathing problems and infants born prematurely.

NCT ID: NCT00421018 Completed - Allergic Asthma Clinical Trials

Optimization of Asthma Treatment Through Exhaled NO for Increased Asthma-Related Quality of Life (NOAK)

Start date: November 2006
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether use of exhaled NO (nitric oxide) to regulate the anti-inflammatory treatment leads to increased asthma-related quality of life in patients with allergic asthma

NCT ID: NCT00419952 Completed - Asthma Clinical Trials

A Comparison of SYMBICORT® pMDI With Budesonide HFA pMDI in African American Subjects With Asthma.

Start date: February 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the effectiveness and safety of SYMBICORT® pMDI (a medication approved by the Food and Drug Administration, FDA) in the African American population.

NCT ID: NCT00419757 Completed - Asthma Clinical Trials

An Efficacy Study Comparing SYMBICORT® Pressurised Metered Dose Inhaler (pMDI) With Budesonide Hydrofluoroalkanes (HFA) pMDI, in Hispanic Subjects With ICS Dependent Asthma

Start date: January 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the effectiveness and safety of SYMBICORT® pMDI (a medication approved by the Food and Drug Administration(FDA)) in the Hispanic population.

NCT ID: NCT00419588 Completed - Asthma Clinical Trials

Growth of Airways and Lung Tissues in Premature and Healthy Infants

Start date: September 2006
Phase:
Study type: Observational

The purpose of this study is to evaluate the growth of the lung and how easily gas can be taken up by the lung in healthy infants born at full term without any breathing problems and infants born prematurely.

NCT ID: NCT00419237 Completed - Asthma Clinical Trials

Investigating The Pharmacokinetics Of An Inhaled Dose Of A New Corticosteroid In Patients With Impaired Liver Function

Start date: January 13, 2005
Phase: Phase 1
Study type: Interventional

The proposed study is designed to investigate the pharmacokinetics, pharmacodynamics (as measured by serum cortisol) and safety of GW685698X in subjects with moderate hepatic impairment and in healthy subjects following a single oral inhaled dose of GW685698X. From the study results it should be possible to assess if there is an altered Risk: Benefit in patients with moderate hepatic impairment

NCT ID: NCT00414817 Active, not recruiting - Asthma Clinical Trials

Telephone-Based Program to Promote Inhaled Corticosteroid Adherence Among Individuals With Asthma

Start date: June 2007
Phase: N/A
Study type: Interventional

Inhaled corticosteroids (ICS) are often prescribed as a treatment for asthma. However, many individuals who take these medications do not adhere to their prescribed treatment regimen. The purpose of this study is to evaluate the effectiveness of a telephone-based program at improving medication adherence among individuals with asthma.