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Asthma clinical trials

View clinical trials related to Asthma.

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NCT ID: NCT00565591 Completed - Allergic Asthma Clinical Trials

Study Mild Intermittent Asthma to Assess the Topical Safety and Tolerability of Albuterol Sulfate Acu-30™ DPI

Start date: November 2007
Phase: Phase 1
Study type: Interventional

This open label single blind study will determine the safety of albuterol sulfate dry powder in a novel inhaler by observing for the potential occurrence of reflex bronchial constriction after inhalation of increasing doses of the compound.

NCT ID: NCT00565266 Completed - Asthma Clinical Trials

Asthma Clinical Research Network (ACRN) Trial - Tiotropium Bromide as an Alternative to Increased Inhaled Corticosteroid in Patients Inadequately Controlled on a Lower Dose of Inhaled Corticosteroid (TALC)

TALC
Start date: May 2008
Phase: Phase 3
Study type: Interventional

Typically, people with asthma are initially prescribed a low dose of inhaled corticosteroid (ICS) medication to control asthma symptoms. If a low dose of ICS is ineffective at controlling symptoms, the addition of a second controller medication is recommended. This study will examine the effectiveness of the medication tiotropium bromide combined with a low dose of ICS at maintaining asthma control in people with moderately severe asthma.

NCT ID: NCT00563056 Completed - Asthma Bronchiale Clinical Trials

An Open, Randomised, Parallel Group Multicentre Study to Compare the Efficacy and Safety of Flutiform® pMDI vs Fluticasone pMDI Plus Formoterol DPI in Adolescent and Adult Subjects With Mild to Moderate-severe Persistent, Reversible Asthma

Start date: September 2007
Phase: Phase 3
Study type: Interventional

Flutiform® compared with the individual components Flixotide® (Fluticasone) and Foradil® (Formoterol) in adolescent and adult patients.

NCT ID: NCT00562991 Completed - Asthma Clinical Trials

Monitoring Asthma Treatment Using Exhaled Nitric Oxide

NOASTHMA
Start date: October 1, 2007
Phase:
Study type: Observational

Asthma is a chronic inflammatory condition in which the airways develop increased responsiveness to various stimuli such as exposure to an allergen, cold air or exercise. It is characterized by airway hyper-responsiveness, inflammation, increased mucus production, and airway obstruction. Since inflammation is an important feature of asthma, the use of non-invasive tests to measure lung inflammation to monitor asthma are of interest.The purpose of the study is to relate costs associated with healthcare utilization and loss of work and school time to the primary health outcome of cumulative number of symptom-free days. This will enable the researchers to determine whether the costs of monitoring exhaled NO to regular management strategy in recently diagnosed asthma will be offset by reductions in other costs of asthma-related care, and, if not, whether the additional costs are likely to be acceptable in terms of the improvement in health outcomes as measured by the additional number of symptom-free days.

NCT ID: NCT00562081 Terminated - Asthma Clinical Trials

The Virtual Asthma Clinic

VAC
Start date: March 2005
Phase: Phase 4
Study type: Interventional

Patients with asthma can be effectively treated using an Internet-based management system as demonstrated by: 1. Physician utilization (emergency department visits and unscheduled physician visits). 2. Health-related quality of life scores. 3. Global health care costs. 4. Frequency of severe exacerbations and time to first exacerbation. 5. Asthma control days. 6. Patient education. Effective patient education will be associated with decreased markers of inflammation and improved indices of airways function.

NCT ID: NCT00559689 Completed - Asthma Clinical Trials

Study of Inhaled Glucocorticosteroid Administration in Asthma Patients

Start date: November 2005
Phase: Phase 4
Study type: Observational

Once-daily inhaled glucocorticosteroids treatment can sufficiently control airway inflammation in asthma patients.

NCT ID: NCT00559546 Completed - Asthma Clinical Trials

Montelukast as a Controller of Atopic Syndrome

MONTAS
Start date: March 2007
Phase: Phase 4
Study type: Interventional

The purpose of the study is to find out if montelukast can be used to treat the various symptoms of allergic syndrome.

NCT ID: NCT00557895 Terminated - Asthma Clinical Trials

Evaluation and Long-Term Follow-Up of Patients With Allergic and Inflammatory Disorders

Start date: August 26, 1996
Phase:
Study type: Observational

This study will evaluate and follow patients with various allergic, hypersensitivity and inflammatory disorders. The protocol is not designed to test new treatments; patients will be managed with standard of care therapies. Participants may be referred to other current NIAID protocols as appropriate or to new studies as they are developed, but will not be required to join another study. Patients with allergic, hypersensitivity or inflammatory disorders between the ages of 3 years and 80 years may be eligible for this study. Conditions of interest include, but are not limited to, asthma, allergic rhinitis, mastocytosis, atopic dermatitis and food allergy. Participants will have a medical history and physical examination, plus standard tests for diagnosing and treating their specific disorder. Tests may include routine blood and urine studies, X-rays or other imaging studies, allergy skin tests and lung function tests. Blood samples may be collected for research on immune system cells and other substances involved in immune function. Generally, about 2 to 6 tablespoons will be drawn at a time, but no more than 16 ounces will be collected over a 6-week period. NIH does not provide emergency medical treatment or treatment for other, unrelated conditions the patient may have. Therefore, patients must maintain a personal physician for these purposes.

NCT ID: NCT00557700 Completed - Asthma Clinical Trials

Study to Investigate the Effect of Inhaled Tiotropium Bromide on Neurokinin-A Induced Bronchoconstriction in Patients With Mild-to-moderate Asthma

Start date: January 2008
Phase: Phase 2
Study type: Interventional

This trial compares the outcome of treatment of mild to moderate asthma: inhaled tiotropium bromide versus placebo.

NCT ID: NCT00557440 Completed - Asthma Clinical Trials

Investigation of the 24 Hour Forced Expiratory Flow in 1 Second (FEV1) Profile of a Single Dose of Indacaterol/Mometasone Delivered Via the TWISTHALER® Device in Adult Patients With Persistent Asthma

Start date: November 2007
Phase: Phase 2
Study type: Interventional

This study is designed to provide data about the 24 hours FEV1 profile, safety and tolerability of indacaterol/mometasone TWISTHALER device compared to placebo and using fluticasone/salmeterol as an active control.