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Asthma clinical trials

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NCT ID: NCT01061424 Completed - Asthma Clinical Trials

The Community United to Challenge Asthma

Project CURA
Start date: October 2009
Phase: N/A
Study type: Interventional

This study compares an asthma self-management intervention, delivered to the family and tailored to their needs and cultural beliefs, to standard asthma education in high-risk Puerto Rican children in elementary school. The primary outcomes are asthma medication adherence and trigger reduction.

NCT ID: NCT01061333 Completed - Asthma Clinical Trials

Early Airway Response to Allergen in Asthmatics (MK-0000-176)

Start date: June 2010
Phase: Phase 1
Study type: Interventional

This study will assess the Early Airway Response (EAR) associated change in forced expiratory volume in one second (FEV1) and plasma 9α-11ß-PGF2 ('9P') after single dose pretreatment of nedocromil, montelukast, and mometasone.

NCT ID: NCT01058863 Completed - Asthma Clinical Trials

A Dose-ranging Study to Evaluate Albuterol and Hydrofluoroalkane in Subjects Ages 12 and Older With Persistent Asthma

Start date: February 2010
Phase: Phase 2
Study type: Interventional

This study is examining how well a dry powder inhaler (DPI) of albuterol medication works to help adult and adolescent subjects 12 years of age and older with persistent asthma to improve lung function.

NCT ID: NCT01057927 Completed - Asthma Clinical Trials

Safety and Efficacy Study of OC000459 Dosed Twice Daily for 28 Days in Asthmatic Subjects

Start date: January 2007
Phase: Phase 2
Study type: Interventional

The purpose of the study is to investigate the clinical effects of multiple (28 day) twice-daily doses of OC000459 in comparison to placebo on clinic lung function (FEV1) in mild to moderate asthmatics with an FEV1 of 60-80% of predicted and requiring only short acting inhaled B2-adrenergic agonists for symptomatic control.

NCT ID: NCT01057875 Completed - Asthma Clinical Trials

Effects of Caffeine on Methacholine Challenge and Exhaled Nitric Oxide Levels.

Start date: January 2010
Phase: N/A
Study type: Interventional

To investigate whether or not the ingestion of caffeine with alter airway responsiveness to methacholine and/or change the level of exhaled nitric oxide.

NCT ID: NCT01057615 Completed - Asthma Clinical Trials

Effect of Fish Oil and Vitamin C on Exercise-Induced Bronchoconstriction and Airway Inflammation in Asthma

Start date: March 2010
Phase: Phase 1
Study type: Interventional

Combining fish oil and vitamin C supplementation will provide a greater anti-inflammatory effect against developing exercise-induced bronchoconstriction (EIB) than either nutritional supplement alone.

NCT ID: NCT01057498 Completed - Asthma Clinical Trials

Safety Study of Nebulized RNS60 to Treat Asthma.

Start date: May 2010
Phase: Phase 1
Study type: Interventional

The purpose of this study is two-fold. First, to determine whether nebulized RNS60 is safe in healthy human subjects and in subjects with mild asthma, in a single-dose administration. Second, to determine whether nebulized RNS60 is safe in human subjects with mild-to-moderate asthma over a 4-week period.

NCT ID: NCT01056692 Completed - Bronchial Asthma Clinical Trials

OC000459 Bronchial Allergen Challenge

Start date: February 2006
Phase: Phase 2
Study type: Interventional

OC0000459 reduces inflammation in the tissues in response to allergic stimuli in patients with asthma. This clinical trial, in mildly asthmatic patients, studies the effects of OC000459 and placebo on the asthmatic response to two known stimulants of the asthmatic response in the lungs, namely cat hair, pollen or house dust mite and methacholine.

NCT ID: NCT01056159 Completed - Asthma Clinical Trials

A Cumulative Dose Study to Evaluate the Safety and Efficacy of Albuterol in a Dry Powder Inhaler and an HFA MDI (Hydrofluoroalkane Metered Dose Inhaler)

Start date: January 2010
Phase: Phase 1
Study type: Interventional

The study will measure the improvement in lung function in subjects with asthma after inhaling from two inhalers, Albuterol in a dry powder inhaler and albuterol in an HFA (hydrofluoroalkane), metered dose inhaler.

NCT ID: NCT01055041 Completed - Clinical trials for Moderate to Severe Persistent Bronchial Asthma

Controller Medications in the Management of Bronchial Asthma

Start date: December 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to know the effect of another controller medication add on to the inhaled corticosteroid and long acting β2 agonist on clinical symptom, lung function and compliance in patients of moderate to severe persistent bronchial asthma.