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Asthma clinical trials

View clinical trials related to Asthma.

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NCT ID: NCT00569192 Completed - Asthma Clinical Trials

A Study of 2 Doses of MAP0010 and Placebo in Asthmatic Children

Start date: December 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to examine the safety and efficacy of two doses of MAP0010 versus placebo in asthmatic infants and children, 12 months to 8 years of age, over a 12-week treatment period.

NCT ID: NCT00567476 Completed - Asthma Clinical Trials

Omalizumab Use and Asthma-Related Quality of Life in Patients With Severe Persistent Allergic Asthma

Start date: November 2007
Phase: Phase 4
Study type: Interventional

This study investigated asthma-related quality of life in Brazilian patients using omalizumab.

NCT ID: NCT00565955 Completed - Bronchial Asthma Clinical Trials

Effect of Addition of Oral Montelukast to Standard Treatment in Acute Moderate to Severe Asthma in Children

Montelukast
Start date: March 2007
Phase: Phase 3
Study type: Interventional

Available evidences show a role of oral montelukast in acute asthma. Safety of oral montelukast is well established in children, as evidenced by use of oral montelukast in long term management of asthma. Therefore, the investigators planned this study to see the effect of oral montelukast as add on therapy to standard treatment in acute moderate to severe asthma in children between 5-15 years of age. HYPOTHESIS: Addition of single dose of oral montelukast to standard therapy in acute moderate to severe asthma in children aged 5-15 years will reduce the modified pulmonary index score to less than 9 in 90% children compared to 70% in children receiving a placebo.

NCT ID: NCT00565591 Completed - Allergic Asthma Clinical Trials

Study Mild Intermittent Asthma to Assess the Topical Safety and Tolerability of Albuterol Sulfate Acu-30™ DPI

Start date: November 2007
Phase: Phase 1
Study type: Interventional

This open label single blind study will determine the safety of albuterol sulfate dry powder in a novel inhaler by observing for the potential occurrence of reflex bronchial constriction after inhalation of increasing doses of the compound.

NCT ID: NCT00565266 Completed - Asthma Clinical Trials

Asthma Clinical Research Network (ACRN) Trial - Tiotropium Bromide as an Alternative to Increased Inhaled Corticosteroid in Patients Inadequately Controlled on a Lower Dose of Inhaled Corticosteroid (TALC)

TALC
Start date: May 2008
Phase: Phase 3
Study type: Interventional

Typically, people with asthma are initially prescribed a low dose of inhaled corticosteroid (ICS) medication to control asthma symptoms. If a low dose of ICS is ineffective at controlling symptoms, the addition of a second controller medication is recommended. This study will examine the effectiveness of the medication tiotropium bromide combined with a low dose of ICS at maintaining asthma control in people with moderately severe asthma.

NCT ID: NCT00563056 Completed - Asthma Bronchiale Clinical Trials

An Open, Randomised, Parallel Group Multicentre Study to Compare the Efficacy and Safety of Flutiform® pMDI vs Fluticasone pMDI Plus Formoterol DPI in Adolescent and Adult Subjects With Mild to Moderate-severe Persistent, Reversible Asthma

Start date: September 2007
Phase: Phase 3
Study type: Interventional

Flutiform® compared with the individual components Flixotide® (Fluticasone) and Foradil® (Formoterol) in adolescent and adult patients.

NCT ID: NCT00562991 Completed - Asthma Clinical Trials

Monitoring Asthma Treatment Using Exhaled Nitric Oxide

NOASTHMA
Start date: October 1, 2007
Phase:
Study type: Observational

Asthma is a chronic inflammatory condition in which the airways develop increased responsiveness to various stimuli such as exposure to an allergen, cold air or exercise. It is characterized by airway hyper-responsiveness, inflammation, increased mucus production, and airway obstruction. Since inflammation is an important feature of asthma, the use of non-invasive tests to measure lung inflammation to monitor asthma are of interest.The purpose of the study is to relate costs associated with healthcare utilization and loss of work and school time to the primary health outcome of cumulative number of symptom-free days. This will enable the researchers to determine whether the costs of monitoring exhaled NO to regular management strategy in recently diagnosed asthma will be offset by reductions in other costs of asthma-related care, and, if not, whether the additional costs are likely to be acceptable in terms of the improvement in health outcomes as measured by the additional number of symptom-free days.

NCT ID: NCT00559689 Completed - Asthma Clinical Trials

Study of Inhaled Glucocorticosteroid Administration in Asthma Patients

Start date: November 2005
Phase: Phase 4
Study type: Observational

Once-daily inhaled glucocorticosteroids treatment can sufficiently control airway inflammation in asthma patients.

NCT ID: NCT00559546 Completed - Asthma Clinical Trials

Montelukast as a Controller of Atopic Syndrome

MONTAS
Start date: March 2007
Phase: Phase 4
Study type: Interventional

The purpose of the study is to find out if montelukast can be used to treat the various symptoms of allergic syndrome.

NCT ID: NCT00557700 Completed - Asthma Clinical Trials

Study to Investigate the Effect of Inhaled Tiotropium Bromide on Neurokinin-A Induced Bronchoconstriction in Patients With Mild-to-moderate Asthma

Start date: January 2008
Phase: Phase 2
Study type: Interventional

This trial compares the outcome of treatment of mild to moderate asthma: inhaled tiotropium bromide versus placebo.