Arterial Hypertension Clinical Trial
Official title:
Effect of Nitrate Supplementation on Blood Pressure and Systemic Microvascular Function of Resistant Hypertensive Patients
Arterial hypertension (AH) has been identified as an important public health problem and considered a new epidemic with high mortality and morbidity. High blood pressure (BP) levels increase the chances of coronary artery disease (CAD), heart failure (HF), stroke, chronic renal failure (CRF) and death. Beetroot powder may be an easier way to increase the availability of nitric oxide and consequently vasodilation in these patients. However, studies are needed to evaluate its benefits in patients with AH.
Status | Recruiting |
Enrollment | 50 |
Est. completion date | June 2025 |
Est. primary completion date | January 2025 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 75 Years |
Eligibility | Inclusion Criteria: - Resistant hypertension, with a diagnosis described in the medical record, without changing medications or increasing doses in the last 30 days. Exclusion Criteria: - neoplasms - heart failure - use of medications with nitrate in their formula - patients undergoing renal denervation |
Country | Name | City | State |
---|---|---|---|
Brazil | National Institute of Cardiology | Rio de Janeiro |
Lead Sponsor | Collaborator |
---|---|
National Institute of Cardiology, Laranjeiras, Brazil |
Brazil,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Assessment of blood pressure evolution | Evaluation using Ambulatory Blood Pressure Monitoring: systolic, diastolic and mean arterial pressures | 60 days |
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