Clinical Trials Logo

Clinical Trial Summary

In view of the wide variety of mechanized endodontic instrumentation systems, the ideal would be that the choose of this system based on the anatomical characteristics of the canal and the biological precepts. In teeth with lesions, contaminated dentin should be removed. However, in many systems, the manufacturer's approach disregards the fact that in wider root canal, instruments used in the apical third small diameter (less than 0.40 mm) may not touch the walls at the final apical. Therefore, the establishment of the initial apical file (LAI), the first instrument that measures the resistance of the walls in working length, could be a criterion in the choice of which system to use, and how many files work within the root canals after LAI determination. However, there is a lack of studies that demonstrate that LAI determination affects the degree of cleaning achieved, as well as the impact that LAI-based instrumentation may have on microcracks formation, canal transportation, postoperative pain and quality of obturation.In this way, the investigators propose a study in vivo performed, in patients from 8 to 18 years of age, therefore in large root canals. The protocol recommended by the manufacturer will be compared by means of a prospective randomized clinical trial, with the addition of the XP Endo finisher and with the protocol based on the initial apical file evaluating postoperative pain, exacerbation between the sessions, the quality of the obturation and periapical radiolucency repair. Considering that currently performing endodontic treatments using mechanized instruments is taught in undergraduate courses throughout the country, studies of this nature help the execution of a endodontics more critical and effective.


Clinical Trial Description

Infected root canal treatments will be performed in two sessions with a TF Adaptive system (Protocol recommended by manufacturer (Group Control) vs. Protocol based on the initial apical file). The root canals will be completed after 14 days. Patients will record postoperative pain during the follow-up period (7 days) using a Visual analogue scale (VAS) and the change in periapical radiolucency will be assessed by periapical index (PAI) scores. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03243357
Study type Interventional
Source Federal University of Uberlandia
Contact Camilla C Gomes Moura, PhD
Phone +55 34 99924 9586
Email camillahistologia@yahoo.com.br
Status Recruiting
Phase N/A
Start date November 22, 2017
Completion date November 3, 2020

See also
  Status Clinical Trial Phase
Completed NCT04552132 - Postoperative Pain and Healing in Teeth Treated With GentleWave or EndoActivator N/A
Completed NCT04514991 - Bone Regenerative Techniques in Endodontic Microsurgery N/A
Withdrawn NCT04104789 - Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - General Phase 2
Completed NCT01904552 - Accuracy of ERCLMDs in Teeth With Apical Periodontitis Phase 1
Completed NCT05792787 - Association Between Apical Periodontitis and Atherosclerotic Cardiovascular Diseases
Completed NCT06072742 - Effect of Lifestyle on Caries and Apical Periodontitis
Completed NCT06226740 - Effectiveness of Different Obturation Techniques N/A
Completed NCT04126928 - Validation of PUFA Index in Assessing Untreated Dental Caries Among Malaysian Adult Subpopulation N/A
Recruiting NCT05439330 - Application of a Dental-dedicated MRI in the Diagnosis of Temporomandibular Joint Disorders, Tissue Alterations Related to Third Molars, Periapical and Periodontal Inflammatory Diseases, and Implant Treatment Planning N/A
Recruiting NCT06005545 - A Study to Compare Various Root Canal Cleaning Devices Based on Cavitation,Ultrasonic and Conventional Methods. N/A
Completed NCT02681276 - Clinical and Microbiological Evaluation of 0.5% Versus 3% Sodium Hypochlorite in Root Canal Treatment N/A
Completed NCT04072926 - Effects of PDT and Bioceramic Filling on Periapical Healing and Postoperative Pain After Endodontic Retreatment Early Phase 1
Completed NCT03711942 - Comparison of Healing of Apical Periodontitis in Periodontally Diseased and Healthy Patients. N/A
Completed NCT03171376 - Effect of Coronal Extent of Obturation on Endo-perio Lesions N/A
Completed NCT03409887 - Effect of Intraorifice Barrier on Healing of Apical Periodontitis N/A
Recruiting NCT06043453 - Revitalization of Traumatized Immature Permanent Teeth
Completed NCT03987659 - Therapeutic Irrigation Procedures to Treat Apical Periodontitis N/A
Completed NCT03288467 - Effect of Sodium Hypochlorite Concentration on Success of Non-surgical Root Canal Treatment N/A
Recruiting NCT03527602 - FE in Anterior Teeth N/A
Completed NCT04545307 - Transplantation of Allogeneic MSC in Patients With Pulp Necrosis and Chronic Apical Periodontitis Phase 2/Phase 3