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Aphasia, Acquired clinical trials

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NCT ID: NCT06405594 Not yet recruiting - Stroke Clinical Trials

Neurocognitive Mechanisms of Sentence Production Impairment in Aphasia

sentence
Start date: June 2024
Phase:
Study type: Observational

The proposed research is relevant to public health because stroke is a leading cause of long-term disability among older adults and communication impairments resulting from stroke have a significant negative impact on quality of life. By seeking to better understand post-stroke aphasia, this project lays the groundwork for development of new interventions, and aligns with NIDCD's priority areas 1 (understanding normal function), 2 (understanding diseases), and 3 (improving diagnosis, treatment, and prevention).

NCT ID: NCT06092814 Not yet recruiting - Stroke Clinical Trials

tACS to Enhance Language Abilities

Start date: June 1, 2024
Phase: N/A
Study type: Interventional

The goal of this study is to see if transcranial alternating current stimulation (tACS) can be used to enhance language abilities in people with post-stroke aphasia. Participants will receive real and sham tACS in conjunction with various language tests. Researchers will compare the post-stroke aphasia group with aged matched controls to see if brain response to tACS differs between groups.

NCT ID: NCT05667480 Not yet recruiting - Chronic Stroke Clinical Trials

VR and Script Training of PWA

Start date: January 2023
Phase: N/A
Study type: Interventional

The goal of this intervention study is to investigate the effects of immersive virtual reality in rehabilitation of language and communication of individuals with post-stroke aphasia. The main research questions are: 1. Is VR-based script training a feasible treatment to Cantonese-speaking PWA? 2. Will VR-based script training, when compared to conventional script training, better enhance treatment outcomes in functional communication of PWA? Participants will be assessed before, in the middle of, immediately after treatment and 8-week post treatment in terms of their performance on: 1. Accuracy and time for producing trained scripts. 2. Accuracy and time for producing un-trained scripts 3. Standardized aphasia test on severity of language impairment 4. Standardized aphasia test on functional communication The participants will be randomly allocated to receive one of the treatment: 1. Virtual reality-based computerized script training; or 2. Computerized script training without virtual reality Researchers will compare the treatment outcomes of the two treatment conditions and see if treatment with virtual reality would better promote outcomes when compared to training without virtual reality.

NCT ID: NCT05572385 Not yet recruiting - Aphasia, Acquired Clinical Trials

Clinic and Neurophysiology of Aphasia Treatment

AphasRehab
Start date: July 1, 2023
Phase: N/A
Study type: Interventional

In the planned study, clinical and electrophysiological features of aphasia recovery in stroke patients are investigated.

NCT ID: NCT04828759 Not yet recruiting - Aphasia, Acquired Clinical Trials

Virtual Reality in Aphasia Telerehabilitation

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

The main purpose of this study is to evaluate the use of the immersive 3D HMD VR technology in the language intervention with a home-based telerehabilitation approach for people with aphasia. The assessments will be conducted at the baseline (prior the intervention periods) and after each intervention period (i.e. after the VR-intervention period and the waitlist period).

NCT ID: NCT04080817 Not yet recruiting - Stroke, Acute Clinical Trials

Neolexon® Aphasia-App in Acute Aphasia After Stroke

Lexi
Start date: October 1, 2019
Phase: N/A
Study type: Interventional

Up to now there is proven evidence of traditional logopedic therapy in aphasia, but recent computer-based algorithms also showed their evidence so far. Due to small and heterogenous study populations further trials are urgently needed. This prospective, randomized, clinical & experimental controlled noninvasive study is intended to provide data for the therapy of an individual approach in aphasia patients.