Clinical Trials Logo
  1. Home
  2. Aortic Coarctation
  3. NCT01340378

A Pilot Study of Thrombin Generation Changes in Neonates Undergoing Placement of a Blalock-Taussig Shunt

Aortic Coarctation Clinical Trial

Official title:
A Pilot Study of Thrombin Generation Changes in Neonates Undergoing Placement of a Blalock-Taussig Shunt

Clinical Trial Summary

The primary goal of this investigation is to describe perioperative thrombin generation in neonates undergoing placement of a Blalock-Taussig (BT) shunt to better understand the coagulation changes that precipitate postoperative shunt occlusion.

Clinical Trial Description

To accomplish our goal, the investigators will measure preoperative levels of one major procoagulant (prothrombin) and one major anticoagulant (Antithrombin). The investigators will also measure preoperative and postoperative thrombelastograms (TEG) and preoperative and postoperative thrombin generation curves (TGC). ;

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01340378
Study type Observational
Source Emory University
Contact
Status Completed
Phase N/A
Start date January 2010
Completion date December 2014
View Details
See also
  Status Clinical Trial Phase
Enrolling by invitation NCT02591940 - Proof of Concept of Model Based Cardiovascular Prediction N/A
Completed NCT02700737 - Evaluation of Image-Based Modelling on Clinical Decisions in Coarctation of the Aorta N/A
Active, not recruiting NCT02739087 - Radiation-Free Heart Catheterization Using MRI N/A
Recruiting NCT03262753 - Long-term Outcomes and Vascular Evaluation After Coarctation of the Aorta Treatment N/A
Completed NCT01278303 - Covered CP Stents for the Prevention or Treatment of Aortic Wall Injury Associated With Coarctation of the Aorta Phase 2
Completed NCT03999073 - Carotid Atherosclerosis in Patients With Aortic Coarctation
Completed NCT01032876 - Cerebral Perfusion During Neonatal Cardiac Surgery N/A
Recruiting NCT05203874 - Contribution of Multimodal Imaging in Early Coarctation
Recruiting NCT03147014 - Cardiovascular Response to Maternal Hyperoxygenation in Fetal Congenital Heart Disease N/A
Completed NCT04330755 - Levosimendan Versus Combination With Magnesium Sulphate on Spine Protection by NIRS in Infants Undergoing Coarctectomy Phase 4
Completed NCT04128540 - Erector Spinae Plane Block Versus Fentanyl Infusion in Pediatric Patients Undergoing Aortic Coarcitectomy Phase 3
Not yet recruiting NCT04307888 - Spanish Percutaneous Aortic INtervention REGISTRY (SPAIN REGISTRY)