Silent Brain Infarction After Endovascular Arch Procedures

Status Completed

Clinical Trial Summary

This is the largest study to evaluate incidence and distribution of silent cerebral infarction (SBI) following endovascular repair for disease of the aortic arch. Also, it is the first cohort to include total endovascular arch repair and devices flushed with carbon dioxide (CO2) to prevent gaseous cerebral embolization.

Clinical Trial Description

Introduction. Poor data exist concerning the rate of silent cerebral ischemic events following endovascular treatment of the aortic arch. The objective of this work was to quantify these lesions using the STEP registry.

Methods. This multicentre retrospective cohort study included consecutive patients treated with an aortic endoprosthesis deployed in Ishimaru zone 0 to 3 and brain diffusion-weighted magnetic resonance imaging (DW-MRI) within 7 days after the procedure. DW-MRI was performed to identify the location and number of new silent brain infarctions (SBI), microbleeds ans general outcome of the patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04489277
Study type	Observational [Patient Registry]
Source	Medical University of Vienna
Contact
Status	Completed
Phase
Start date	September 1, 2018
Completion date	January 31, 2020

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