Anxiety Clinical Trial
Official title:
Effects of Trauma and Discrimination on the Social Regulation of Threat-related Vigilance and Arousal
This study will examine the effects of social support on threat vigilance and arousal using eye tracking. We will also test the moderating effects of trauma and discrimination history.
Status | Not yet recruiting |
Enrollment | 45 |
Est. completion date | December 2026 |
Est. primary completion date | December 2026 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 65 Years |
Eligibility | Inclusion Criteria: - In a stable romantic relationship for 6 months or more - Normal vision or corrected-to-normal vision - Fluent in English Exclusion Criteria: - If vision is corrected-to-normal, needs to use hard contact lenses, bifocal contact lenses, or glasses - Experienced a traumatic event within the past 4 weeks |
Country | Name | City | State |
---|---|---|---|
United States | University of Nevada, Reno | Reno | Nevada |
Lead Sponsor | Collaborator |
---|---|
University of Nevada, Reno |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Vigilance Related Eye Movements - Number of Eye Fixations | Participants will view 15 pictures of natural environmental scenes for 10 seconds per image. We will use an eye tracker to examine the number of eye fixations per scene. A greater number of fixations during the 10 second presentation of a scene would indicate greater vigilance. | Collected from minute 15 to minute 45 of study participation, approximately | |
Primary | Vigilance Related Eye Movements - Visual Scanning | Participants will view 15 pictures of natural environmental scenes for 10 seconds per image. We will use an eye tracker to examine the proportion of the scene that they look at (fixate on) out of approximately 80 possible sectors. A greater proportion of the scene they fixate on would indicate greater vigilance. | Collected from minute 15 to minute 45 of study participation, approximately | |
Primary | Threat-Related Physiological Arousal - Pupil Dilation | Participants will view a series of visual cues (either an 'X' or an 'O') where an 'X' signals a possible (20% probability) aversive auditory stimulus (human scream). We will examine pupil dilation during the task in order to measure arousal in response to uncertain threat. We will calculate average pupil dilation during the wait period after threat cues (X) and after safety cues (O). We will subtract average pupil dilation after safety cues from threat cues to create an index of threat-related arousal. Greater pupil dilation (for threat minus safety cues) would indicate greater threat-related arousal. | Collected from minute 45 to minute 75 of study participation, approximately |
Status | Clinical Trial | Phase | |
---|---|---|---|
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