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Effects of SRX246 on an Experimental Model of Fear and Anxiety in Humans

Anxiety Clinical Trial

Official title:
Effects of SRX246, a Vasopressin Receptor (V1a) Antagonist, on an Experimental Model of Fear and Anxiety in Humans

Clinical Trial Summary

To determine the effects of SRX246 on fear and anxiety based on fear-potentiated startle in humans. Additionally, the effects of the compound on emotion recognition will be explored.

Clinical Trial Description

The study will use a double-blind, cross-over design in which each subject will receive placebo and SRX246 for 5-7 days before testing (given in counter-balanced order). The study will examine the effect of the drug on the potentiation of startle using a well-established paradigm that involves anticipation of no-shock, predictable shock, and unpredictable shock. Drug effects on emotion recognition will also be explored. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02922166
Study type Interventional
Source Azevan Pharmaceuticals
Contact
Status Active, not recruiting
Phase Phase 1
Start date February 3, 2017
Completion date December 2019
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