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Hydroxychloroquine for the First Thrombosis Prevention in Antiphospholipid Antibody Positive Patients

Antiphospholipid Syndrome Clinical Trial

Official title:
A Prospective Randomized Controlled Trial of Hydroxychloroquine in the Primary Thrombosis Prophylaxis of aPL Positive But Thrombosis-free Patients.

Clinical Trial Summary

In this multi-center international study, our aim is to determine the effectiveness of HCQ for primary thrombosis prophylaxis in persistently aPL-positive but thrombosis-free patients without systemic autoimmune diseases.

Clinical Trial Description

Randomized to receive HCQ or no treatment in addition to their standard regimen. 11 study visits and 10 phone visits over 5 years. This study was terminated at 2 years due to low recruitment rate exacerbated by manufacturing shortage and price increase of hydroxychloroquine. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01784523
Study type Interventional
Source Hospital for Special Surgery, New York
Contact
Status Terminated
Phase Phase 3
Start date February 2013
Completion date September 30, 2015
View Details
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