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Aneurysm clinical trials

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NCT ID: NCT05186649 Recruiting - Mitral Stenosis Clinical Trials

Left Atrial Appendage (LAA) Clot With Severe Mitral Stenosis

Start date: December 1, 2021
Phase:
Study type: Observational

Consecutive patients with severe mitral stenosis and clot in left atrial appendage (LAA) on transesophageal echocardiography fulfilling the inclusion criteria will be recruited for this study. An ACUSON 128-XP echocardiographic system equipped with omniplane and biplane transesophageal probes will be used for this study. TEE followed by CT Angiography will be performed according to the standard procedure after obtaining informed consent.

NCT ID: NCT05183373 Recruiting - Coronary Disease Clinical Trials

Inflammation and Clotting Abnormalities in Aneurysmal Coronary Artery Disease

CARE-ANUERYSM
Start date: January 10, 2022
Phase:
Study type: Observational

The main objective of the CARE-ANEURYSM project is to evaluate inflammation and clotting abnormalities in patients with aneurysmal coronary artery disease in relation to patients with abdominal aortic aneurysm or coronary artery disease (acting as controls).

NCT ID: NCT05179967 Recruiting - Clinical trials for Juxtarenal Abdominal Aortic Aneurysm

Safety and Efficacy Study of WeFlow-JAAA Stent Graft System for Complex Abdominal Aortic Aneurysm(GREAT Study)

Start date: February 23, 2022
Phase: N/A
Study type: Interventional

A prospective, multi-center, objective performance criteria clinical trial to evaluate the safety and efficacy of WeFlow-JAAA stent graft system manufactured by Hangzhou Endonom Medtech Co., Ltd. for the complex abdominal aortic aneurysm.

NCT ID: NCT05172830 Recruiting - Clinical trials for Abdominal Aortic Aneurysm

Hellenic Registry of Ovation Alto™ Abdominal Stent Graft System

Start date: January 1, 2021
Phase:
Study type: Observational [Patient Registry]

This is a Hellenic Registry including both retrospective and prospective subjects receiving the Ovation Alto™ Abdominal Stent Graft System ("Ovation Alto™ Abdominal Stent Graft System Post-Market Study") in the treatment of abdominal aortic aneurysms (AAA). The Ovation Alto™ Hellenic Registry is intended to expand the clinical knowledge base by collecting data on subjects treated with the Ovation Alto™ Abdominal Stent Graft System in actual clinical practice during the first post-operative year.

NCT ID: NCT05171465 Not yet recruiting - Clinical trials for Subarachnoid Hemorrhage

Intrasaccular neCk Occlusion deVice Treatment of Intracranial Aneurysm in Acute Subarachnoid hemorRhAGE

COVERAGE
Start date: March 2022
Phase:
Study type: Observational [Patient Registry]

Rationale: Intrasaccular neck occlusion devices have been used for unruptured aneurysm without safety concerns and good occlusion rates. In the setting of a subarachnoid hemorrhage, they could improve the rate of complete occlusion without safety concerns. Aim: To explore the safety and efficacy of intrasaccular neck occlusion devices in patients with acute subarachnoid hemorrhage caused by a ruptured saccular aneurysm by a one arm prospective registry. Study outcome: The primary outcomes is the rate of complete occlusion (Raymond-Roy I) and rebleeding at one year follow-up. The primary safety outcome is rate of rebleeding during the admission.

NCT ID: NCT05161377 Recruiting - Clinical trials for Middle Cerebral Artery Aneurysm

Middle Cerebral Artery Aneurysm Trial

MCAAT
Start date: May 15, 2022
Phase: N/A
Study type: Interventional

Intracranial aneurysms located on the middle cerebral artery (MCA) are considered by many surgeons to represent a distinct subgroup of aneurysms for which clipping may still be the best management option. Most MCA aneurysms are accessible, proximal control can readily be secured in case of rupture, and clip application can typically proceed without requiring the dissection of perforating arteries. In comparison, certain anatomic features of MCA aneurysms such as a wide neck, often including a branch artery origin, frequently render endovascular management more difficult. New endovascular devices were and continue to be introduced to address these anatomic difficulties, including stents, flow diverters, and intra-saccular flow disruptors (ISFDs) such as the WEB. Thus, while most aneurysms are increasingly treated with endovascular methods, many MCA aneurysm patients are still managed surgically, but convincing evidence of which management paradigm is best is lacking.

NCT ID: NCT05155956 Enrolling by invitation - Clinical trials for Thoracic Aortic Aneurysm

Cerebral Hemodynamics and Microemboli During Placement of Relay®Branch Thoracic Stent-Graft System

CHaMP
Start date: December 15, 2021
Phase:
Study type: Observational

This is an observational cohort study addressing the incidence of cerebral microemboli and alterations of cerebral hemodynamic physiology of the Relay®Branch thoracic stent-graft system.

NCT ID: NCT05155943 Terminated - Clinical trials for Left Atrial Appendage Aneurysm

K2 Medical KALPA X™ Mapping, Imaging and Navigation Device

Start date: December 14, 2020
Phase: N/A
Study type: Interventional

This prospective, multi-center, non-randomized, single-blinded, open-label, single-arm, comparator study will enroll up to 100 eligible subjects from multiple sites undergoing LAAC procedure to evaluate the safety and performance of the KALPA™ mapping, imaging and navigation device in patients undergoing Left Atrial Appendage Closure (LAAC).

NCT ID: NCT05153083 Suspended - Aneurysm Clinical Trials

Cryoablation of Intercostal Nerves for Better Control of Postoperative Pain After Thoracic and Thoracoabdominal Open Surgery

Start date: December 31, 2024
Phase:
Study type: Observational

The purpose of the registry is to evaluate the peri-operative and short- term outcomes of intercostal nerves cryoablation for post-operative pain control after open thoracic and thoracoabdominal aortic aneurysms repair. The cryoablation procedure is one of the opportunities for pain control after thoracotomy. So, it is routinely performed in major several centers in aortic surgery around the world as a part of the TAA and TAAA procedure. The Registry will include approximately 200 patients treated from January 2022 to January 2024 for thoracic or thoracoabdominal aortic aneurysm by means of open surgery and in whom intraoperative intercostal nerves cryoablation will be performed; to reach 200 patients, the enrolments can be extended until January 2027.

NCT ID: NCT05152225 Not yet recruiting - Clinical trials for Endocarditis, Bacterial

Neurological Complication of Infective Endocarditis: A Prospective Multi-site Cohort Study

Start date: January 1, 2022
Phase:
Study type: Observational [Patient Registry]

The main objective of this study is to better estimate the rate of infectious intracranial aneurysms (IIA) in proved infective endocarditis (IE). It also aims to identify MRI markers capable of accurately predicting (or excluding) IIA; to assess the impact of the different MRI abnormalities on the outcome; to capture the real-world management of EI with neurological complications in comprehensive IE centers in France