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Aneurysm clinical trials

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NCT ID: NCT01234610 Completed - Clinical trials for Cardiovascular Disease

Feasibility Study of Exercise Training for Abdominal Aortic Aneurysm Disease

Start date: January 2010
Phase: N/A
Study type: Interventional

An abdominal aortic aneurysm (AAA) is a weakened and enlarged area in the abdominal aorta, which is a large blood vessel in the abdomen. Large AAAs (>55 mm diameter) carry a high risk of rupture, a surgical emergency that often leads to death due to severe internal bleeding. It has been suggested that regular exercise training might limit the rate at which AAAs develop. However, little is known about the safety and effectiveness of exercise training in these patients. This pilot study will examine the feasibility of supervised aerobic exercise training for patients with small AAAs (30 to 49 mm diameter). The investigators hypothesize that exercise training will be safe and useful for patients with small AAAs.

NCT ID: NCT01230684 Terminated - Clinical trials for Endograft Implantation to Repair Abdominal Aortic Aneurysm

Contrast Enhanced Ultrasound vs. Computed Tomographic Angiography in the Detection of Endoleaks Following AAA Repair

Start date: December 2010
Phase: N/A
Study type: Interventional

The purpose of the study is to compare two different types of imaging techniques to identify endoleaks. Following the endovascular procedure, subjects are seen at one month to have computed tomographic angiography (CTA) to confirm the graft is not leaking (endoleak). CTA is the standard imaging technique used to identify endoleaks. This study will investigate if the image technique color duplex ultrasound with contrast enhanced ultrasound (CEUS) is a good tool to identify endoleaks too.

NCT ID: NCT01230203 Completed - Clinical trials for Endovascular Repair of Abdominal Aortic Aneurysm

Computed Tomography Scan Versus Color Duplex Ultrasound for Surveillance of Endovascular Repair of Abdominal Aortic Aneurysm. A Prospective Multicenter Study

ESSEA
Start date: December 16, 2010
Phase: N/A
Study type: Interventional

Cumulative radiation dose, cost, contrast induced nephrotoxicity and increased demand for computed tomography aortography (CTA) suggest that duplex ultrasonoraphy (DU) may be an alternative to CTA-based surveillance. The investigators compared CTA with DU during endovascular aneurysm repair (EVAR) follow-up. Patients undergoing EVAR have radiological follow-up data entered in a prospectively multicenter database. The gold standard test for endoleak detection was CTA. DU interpretation was performed independently of CTA and vice versa.

NCT ID: NCT01225094 Completed - Acute Kidney Injury Clinical Trials

Curcumin to Prevent Complications After Elective Abdominal Aortic Aneurysm (AAA) Repair

Start date: November 2011
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this program of research is to determine whether curcumin, a natural health product, can prevent acute kidney injury and other complications after elective AAA repair. If proven safe and effective, curcumin is an inexpensive intervention which can be readily applied to almost 50,000 AAA repairs performed worldwide each year. New knowledge about this intervention may also guide its use in other surgical and medical settings to prevent complications to the kidneys, heart and other organs.

NCT ID: NCT01211548 Completed - Clinical trials for Complex Aortic Surgery

Coronary CT Angiography in Aneurysms Repaired With Open or Endovascular Approach

CARE
Start date: February 2011
Phase: N/A
Study type: Observational

This proposal is for the pilot study that will inform the conduct of a larger prospective randomized controlled trial to guide perioperative work up and the cost/utility of CTCA (high definition CT coronary angiography.)

NCT ID: NCT01208415 Completed - Iliac Aneurysms Clinical Trials

PRESERVE-Zenith® Iliac Branch System Clinical Study

Start date: January 2011
Phase: N/A
Study type: Interventional

The PRESERVE-Zenith® Iliac Branch System Clinical Study is a clinical trial to study the safety and effectiveness of the Zenith® Branch Endovascular Graft-Iliac Bifurcation in combination with the Zenith® Connection Endovascular Stent/ConnectSX™ covered stent in the treatment of aorto-iliac and iliac aneurysms.

NCT ID: NCT01205945 Recruiting - Clinical trials for Aortic Aneurysm, Abdominal

The Effect of Abdominal Aortic Aneurysm Screening on Mortality in Asian Population

Start date: August 2010
Phase: N/A
Study type: Observational

Abdominal aortic aneurysm(AAA) occurs when the infrarenal aorta expands to a maximal diameter of 3.0cm or greater. Although AAA may asymptomatic for many years, almost one third eventually rupture if left untreated. Several randomized trials showed that ultrasonographic screening for AAA could reduce the frequency of acute operations and AAA-related mortality. However, all of randomized trials were performed in Western countries. There was no randomized trials for AAA screening in Asian countries. This randomized, controlled trial is to analyze the benefits of screening old population for AAA in Korea.

NCT ID: NCT01204268 Recruiting - Brain Ischemia Clinical Trials

The Neuroprotection of Sevoflurane Preconditioning on Intracranial Aneurysm Surgery

Start date: August 2009
Phase: N/A
Study type: Interventional

The current study is designed to clarify the neuroprotective effect of sevoflurane preconditioning on the patients underwent intracranial aneurysm surgery.

NCT ID: NCT01195129 Terminated - Clinical trials for Intracerebral Aneursym

HydroCoil Cerebral Aneurysm Treatment Trial

HCAT
Start date: December 2008
Phase: Phase 4
Study type: Interventional

The study will compare clinical and angiographic outcomes in patients receiving Hydrocoil aneurysm treatment versus patients receiving non-HydroCoil aneurysm treatment.

NCT ID: NCT01194388 Withdrawn - Clinical trials for Intracranial Aneurysm

Axium Coil in Completing Endovascular Aneurysm Surgery Study

ACCESS
Start date: September 2010
Phase:
Study type: Observational

The current observational evaluation is designed to evaluate the performance of the Axium™ MicroFx™ Detachable Coil System for the treatment of intracranial aneurysms in the real life practice.