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Anesthesia clinical trials

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NCT ID: NCT03157479 Completed - Anesthesia Clinical Trials

Intraoperative Protective Ventilation for Obese Patients Undergoing Gynaecological Laparoscopic Surgery

Inprove4large
Start date: May 1, 2017
Phase: N/A
Study type: Interventional

Background. The use of a comprehensive strategy providing low tidal volumes, peep and recruiting maneuvers in patients undergoing open abdominal surgery improves postoperative respiratory function and clinical outcome. It is unknown whether such ventilatory approach may be feasible and/or beneficial in patients undergoing laparoscopy, as pneumoperitoneum and Trendelenburg position may alter lung volumes and chest-wall elastance. Objective. The investigators designed a randomized, controlled trial to assess the effect of a lung-protective ventilation strategy on postoperative oxygenation in obese patients undergoing laparoscopic surgery.

NCT ID: NCT03152513 Completed - Surgery Clinical Trials

A Review of "Anesthesia Stat!" in the Pediatric Operating Room

Start date: March 1, 2017
Phase:
Study type: Observational [Patient Registry]

The objective of this study is to look at critical events in the pediatric operating room in a retrospective and now prospective fashion to determine if there are any trends such as age, presence of URI, type of surgery, type of airway, level of hands on provider, or other predictive markers associated these events so that we may gain some insight into perhaps reducing the incidence of these events or simply be more attune to the increased risks in certain situations.

NCT ID: NCT03151746 Terminated - Anesthesia Clinical Trials

Gabapentin on Postoperative Pain Associated With Ureteroscopy and Stents Insertion

Start date: January 14, 2018
Phase: Phase 4
Study type: Interventional

The study's objective is to determine the efficacy of preoperative gabapentin in relieving postoperative pain, reducing opioid use and improving quality of recovery in subjects undergoing urologic surgery. Investigators hypothesize that subjects receiving gabapentin will have lower pain scores, less opioid consumption and better quality of recovery as compared to subjects who are given a placebo.

NCT ID: NCT03144479 Completed - Anesthesia Clinical Trials

New Technique to Assess Correct Positioning of the Right-sided Double Lumen Tube

Start date: March 10, 2017
Phase: N/A
Study type: Interventional

A technique not yet described in the literature and allowing anesthesiologists who do not regularly practice fibroscopy or who do not routinely have this type of apparatus for their procedures, to install straight double-lumen tubes without compromising the ventilation of the patient. The aim is to introduce a central venous catheter wire guide into the bronchial arm of the right double-lumen tube and insert it into the right upper lobe bronchus orifice under fluoroscopic control. Then, to validate the new technique, we will carry out a fibroscopic control.

NCT ID: NCT03143972 Completed - Anesthesia Clinical Trials

Pharmacodynamic Interaction of REMI and DMED

PIRAD
Start date: June 28, 2017
Phase: Phase 4
Study type: Interventional

The objective is to map the pharmacokinetic / pharmacodynamic interaction between dexmedetomidine and remifentanil by observing changes in anesthetic depth. These changes will be related to drug concentrations using pharmacokinetic/pharmacodynamic (PKPD) modeling.

NCT ID: NCT03142906 Recruiting - Surgery Clinical Trials

Perioperative Point-of-Care Ultrasound

POCUS-RCT
Start date: April 4, 2017
Phase: N/A
Study type: Interventional

The goal of this study is to assess the impact of perioperative point-of-care ultrasound (POCUS) assessment on patient-important outcomes (e.g. hospital length of stay, length of stay in recovery, mortality etc.) and perioperative patient management strategies, in patients undergoing non-elective non-cardiac surgeries.

NCT ID: NCT03140228 Completed - Anesthesia Clinical Trials

Postoperative Sore Throat in Children: Comparison Between Two Supraglottic Devices, Ambu® AuraOnceâ„¢ Laryngeal Mask Airway (LMA) and I-Gel®.

Start date: June 15, 2017
Phase: N/A
Study type: Interventional

Sore throat is minor but well recognized complaint after receiving general anaesthesia. It is rated as 8th most undesirable outcome in postoperative period.It not only affects the patient's satisfaction but also can affect patient activities after leaving hospital. Many factors can contribute to postoperative sore throat and the incidence has been found to vary with the method by which airway is managed. The study is conducted to compare the severity and frequency of postoperative sore throat in children undergoing elective surgery following the use of AmbuAuraOnce LMA and I-Gel. The study will be done in children who are able to self-report the severity of sore throat. This study will help us to determine which supraglottic device (I-gel vs. AmbuAuraOnce LMA) is better in terms of causing less complication spells of sore throat. The use of such device will not only reduce the severity and frequency of postoperative sore throat that may affect the activities of patient after leaving hospital but also will improve satisfaction level of patient and parents.

NCT ID: NCT03128931 Terminated - Anesthesia Clinical Trials

SedLine Engineering Data Collection Study in Pediatric Patients Undergoing General Anesthesia or Sedation

Start date: December 23, 2016
Phase: N/A
Study type: Interventional

The purpose of the study is to collect EEG data with the Masimo SedLine device along with vital signs, patient demographics, anesthetic record and surgical procedure during general anesthesia or sedation.

NCT ID: NCT03127891 Completed - Anesthesia Clinical Trials

Effect of Yoga on Anesthesia Management

yoga
Start date: November 2016
Phase: N/A
Study type: Interventional

TITLE: EFFECT OF SHORT-TERM PRANAYAMA ON ANAESTHESIA MANAGEMENT IN PATIENTS UNDERGOING CARDIAC SURGERY Primary aim: To evaluate the effect of pre-operative short term pranayama yoga on stress-induced hemodynamic (HR, MAP) changes in patients scheduled for cardiac surgery. Secondary aims: 1. To compare the effect of YOGA on preoperative anxiety. 2. To compare the effect of Yoga on SPO2. 3. To compare effect of Yoga on total consumption of propofol administered using Closed Loop Anaesthesia Delivery system(CLADS) 4. To compare effect of Yoga on total consumption of fentanyl, and vecuronium 5. To compare effect of Yoga on post-operative anxiety (after extubation in CTVS ward) 6. To compare effect of Yoga on postoperative outcome in terms of duration of mechanical ventilation, duration of ICU stay, incidence of complications and post-op mortality

NCT ID: NCT03124680 Completed - Anesthesia Clinical Trials

Opioid Free Anesthesia and Continuous Post-operative Pulse Oximetry Monitoring in the Obese Patient

Start date: April 20, 2017
Phase: N/A
Study type: Interventional

Anaesthesia has three major components, analgesia, muscle relaxation and hypnosis. For a long time, opioids have been covering the analgesia function. (1) When using opioids, an analgesic effect is obtained per-operatively, however, not without side-effects. Post-operative complications such as: respiratory depression, post-operative nausea and vomiting, pruritus, acute opioid tolerance and hyperalgesia, difficulty voiding and ileus, are well known. Opioid usage is an important risk factor of postoperative desaturation. Postoperative desaturation can lead to severe hypoxemia and even tissue hypoxia, followed by obvious cardiologic and neurological complications. Thus, in patients at risk, such as the obese patient, experts suggest reducing opioid usage. Non-opiate protocols implemented on the obese patient have been published. Non-opiate protocols have been established using a combination of ketamine, lidocaine and an alpha-2 agonist. The main purpose of this pilot study is to evaluate whether patients undergoing an opioid free anaesthesia regime experience less desaturation episodes during the first 24 h post-bariatric surgery than patients having received an opioid anaesthesia regime.