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Anesthesia clinical trials

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NCT ID: NCT05692167 Recruiting - Anesthesia Clinical Trials

Dexmedetomidine in Topical Versus Peribulbar Anesthesia for Cataract Surgery

Start date: July 15, 2023
Phase: Phase 2
Study type: Interventional

The aim of this study is to compare efficacy of dexmedetomidine as an additive to topical versus peribulbar anesthesia for cataract surgery

NCT ID: NCT05689294 Completed - Anesthesia Clinical Trials

Non Invasive Continuous Blood Pressure Sensor

Start date: April 1, 2023
Phase:
Study type: Observational

The primary objective of this study is to collect training data in order to establish a method for correlating arterial blood pressure with voltage output signals from a non-invasive piezoelectric array sensor placed on the skin superficial to the radial artery.

NCT ID: NCT05688943 Recruiting - Anesthesia Clinical Trials

Comparative Analysis of Spinal Anesthesia Versus General Anesthesia for vNOTES

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

This study compares general anesthesia and spinal anesthesia for vNOTE tubal sterilization. A direct comparison of these methods has not been done before for this surgical approach. Investigators will aim to compare the two methods to determine the differences in perioperative complications, postoperative pain, postoperative nausea and vomiting, and the time to get the patient ready for discharge from the recovery room.

NCT ID: NCT05687253 Completed - Surgery Clinical Trials

Evaluation of Intubation Conditions Following BX1000 or Rocuronium in Subjects Undergoing Surgery

Start date: October 25, 2022
Phase: Phase 2
Study type: Interventional

Assessment of Intubation conditions following administration of neuromuscular blocking agents; BX1000 (investigational) or rocuronium (active control).

NCT ID: NCT05686005 Completed - Anesthesia Clinical Trials

Tranexamic Acid in Functional Endoscopic Sinus Surgery

Start date: December 3, 2022
Phase: Phase 4
Study type: Interventional

The purpose of the study is to compare the effect of oral tranexamic acid vs. intravenous in decreasing bleeding and improving the field during FESS.

NCT ID: NCT05681572 Recruiting - Anesthesia Clinical Trials

Effect of Sedative and Anxiolytic Premedication on Children Experience After General Anesthesia

pediaPREM
Start date: April 18, 2023
Phase: Phase 3
Study type: Interventional

Children undergoing general anesthesia for surgery commonly need sedative and anxiolytic premedication but little clinical evidence supports is benefit for children older than 7 years old. The aim of this prospective randomized clinical trial is to assess the impact of pharmacologic premedication on perioperative children experience.

NCT ID: NCT05672329 Completed - Anesthesia Clinical Trials

Functional Residual Capacity Under Apnoeic Oxygenation With Different Flow Rates in Children

FUTURE
Start date: January 9, 2023
Phase: N/A
Study type: Interventional

During induction of general anaesthesia physiological breathing stops and needs to be artificially established with facemask ventilation, and finally tracheal intubation or placement of a supraglottic airway. During the airway management, when lungs are not or only poorly ventilated, there is a risk for atelectasis. These atelectasis can contribute to respiratory adverse events (e.g. pulmonary infection or respiratory insufficiency) during or after general anaesthesia. High-flow nasal oxygen (HFNO) is the administration of heated, humidified and blended air/oxygen mixture via a nasal cannula at rates ≥ 2 L/kg/min. HFNO used during airway management (i.e. intubation) can extend the tolerance for apnea, the time from end of physiological breathing until artificial ventilation is established. The main objective of this study is thus to investigate the variations of poorly ventilated lung units (i.e., silent spaces) as a surrogate for functional residual capacity measured by electrical impedance tomography to dynamically assess atelectasis formation and regression under apnoeic oxygenation with different flow rates.

NCT ID: NCT05668689 Recruiting - Anesthesia Clinical Trials

URAISE: Ultrasound Regional Anaesthesia Interpretation Skill Evaluation

URAISE
Start date: February 13, 2022
Phase: N/A
Study type: Interventional

Prospective study based on psychometric principles.# To generate a validated test of ultrasound guided regional anaesthesia that can used to differentiate reliably between users of different skill levels. Primary outcome: Development of a validated, reliable and defensible tool to test ultrasound guided regional anaesthesia image interpretation skills. Secondary outcomes: Development a validated, reliable and defensible assessment tool assessing anatomical, clinical knowledge and the performance of ultrasound guided regional anaesthesia: Assessment of anatomical knowledge relevant to performing a local anaesthetic injection around peripheral nerves Assessment of clinical knowledge relevant to regional anaesthesia required to perform a local anaesthetic injection around peripheral nerves Assessment of knowledge relating to the performance of an ultrasound-guided local anaesthetic injection around peripheral nerve

NCT ID: NCT05664386 Recruiting - Anesthesia Clinical Trials

Effect of Ciprofol Infusion for Induction and Maintenance on Hemodynamics and Postoperative Recovery

Start date: April 10, 2023
Phase: Phase 4
Study type: Interventional

To study the Effect of Ciprofol Infusion for Induction and Maintenance of anesthesia on Hemodynamics and Postoperative Recovery in Patients Undergoing Thoracoscopic Lobectomy:a randomized, controlled trial.

NCT ID: NCT05664295 Completed - Anesthesia Clinical Trials

Orexin-A Levels in Insomnia Patients

Start date: December 30, 2022
Phase:
Study type: Observational [Patient Registry]

In the pathophysiology of insomnia, the increase of the orexin-A (OXA) peptide released from orexin neurons in the lateral hypothalamus plays an important role. Orexins takes part at the emergence of anesthesia. In the literature, investigators could not attain any studies about the arousal of insomnia patients from anesthesia. In this study, the effect of this peptide on the emergence process from anesthesia was investigated by comparing plasma OXA levels before and after anesthesia in insomnia patients.