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Anesthesia clinical trials

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NCT ID: NCT06361693 Not yet recruiting - Anxiety Clinical Trials

Descriptive Observational Study of Patient-performed Pre-oxygenation

ApréOx
Start date: May 2024
Phase:
Study type: Observational

The aim of this research would be to determine the efficacy and effects of preoxygenation when performed by the patient (mask held by the patient). This is the concept of "self-preoxygenation".

NCT ID: NCT06357234 Not yet recruiting - Anesthesia Clinical Trials

Aprepitant Treatment to Prevent Postoperative Nausea and Vomiting in Children Undergoing Scoliosis Surgery

Start date: June 2024
Phase: Phase 2
Study type: Interventional

This research trial will measure how useful Aprepitant is in preventing nausea and vomiting in children having surgery to correct scoliosis (curvature of the spine).

NCT ID: NCT06355687 Not yet recruiting - Anesthesia Clinical Trials

Melatonin in Obese Patients in Laparoscopic Cholecystectomy

Start date: April 2024
Phase: N/A
Study type: Interventional

Opioid free anesthesia (OFA) means a technique in which no intraoperative opioid is administered through any route. Perioperative pain management in an obese patient is challenging. The incidence of respiratory depression is higher in obese patients and is exaggerated with opioids, so the investigators are searching for a drug that has analgesic effect without any effect on respiratory function. In this study, the investigators will add melatonin to OFA in obese patients undergoing laparoscopic cholecystectomy.

NCT ID: NCT06346158 Not yet recruiting - Anesthesia Clinical Trials

Prediction of Propofol Effect-Site Concentration Associated With Deep Anesthesia

PRESCOD-AI
Start date: May 2024
Phase:
Study type: Observational

The goal of this observational study is to explore the variability of the concentration at the effect site (Ce) of propofol to reach deep anesthesia (DA) during induction of general anesthesia in adults. The investigators hypothesized that there is a great variability in this Ce that could be precisely explained by - Electroencephalographic (EEG) features available prior to induction of anesthesia - Cognitive performance - Patients characteristics Participants will undergo preoperative cognitive testing and awake EEG. Then, induction of general anesthesia will be performed using continuous infusion of propofol. The Ce at which Deep anesthesia is observed will be recorded.

NCT ID: NCT06333938 Not yet recruiting - Surgery Clinical Trials

Veterans Enhanced Recovery Using Integrative Treatments Around Surgery

VERITAS
Start date: June 2024
Phase: Phase 4
Study type: Interventional

The study aims to assess the effectiveness of NSS2-Bridge in postoperative pain management in comparison to Battlefield Acupuncture (BFA).

NCT ID: NCT06330038 Not yet recruiting - Clinical trials for Non-small Cell Lung Cancer

Anesthesia and Non-small Cell Lung Cancer Recurrence

GASTIVA
Start date: May 1, 2024
Phase: Phase 4
Study type: Interventional

There has been ongoing debate about the relationship between cancer recurrence and anesthetic management. Therefore, the investigators will test the hypothesis that the recurrence free survival (RFS) after curative resection of NSCLC is higher in patient who received total intravenous anesthesia (TIVA) than volatile anesthetics in this multi-center randomized trials.

NCT ID: NCT06317025 Not yet recruiting - Anesthesia Clinical Trials

Design and Development of Multi-modal Intelligent Anesthesia Monitoring System

Start date: May 2024
Phase:
Study type: Observational

This project integrates the characteristics of electroencephalo-graph(EEG), cerebral oxygen, blood pressure, heart rate, etc., based on nonlinear theory and neural oscillation, large sample data and machine learning theory, to develop a multi-modal monitoring system suitable for domestic patients, taking into account changes in sedation, analgesia, cerebral hemodynamics and other factors, regardless of patient age and type of general anesthesia drugs.

NCT ID: NCT06313294 Not yet recruiting - Anesthesia Clinical Trials

Postoperative Follow-up Via Text Messages Automated Versus Telephone in Patients With Continuous Regional Anesthesia

txt-RA
Start date: May 31, 2024
Phase: N/A
Study type: Interventional

Monitoring performed by a trained operator has proven to be useful and valued by patients after the use of continuous regional anesthesia. A health professional calls each patient to gather information about their recovery. However, this direct communication strategy requires time and resources, especially if many patients are involved. A modern and convenient approach involves the use of immediate communication technology for follow-up after a procedure. They may contain specific questions that patients can easily answer from their mobile devices. Automated text messages could be associated with greater convenience and ease for patients with response rates at least like the traditional method. Phone calls, on the other hand, may be less scalable and require more human resources. The objective of the project is to evaluate the feasibility of monitoring through automated electronic messaging by evaluating its usability using a validated scale in Spanish. response rate on the first day and adherence rate compared to that of the traditional method. Secondarily, adherence and differences in satisfaction will be compared.

NCT ID: NCT06303518 Not yet recruiting - Anesthesia Clinical Trials

End Tidal Carbon Dioxide Concentration and Depth of Anesthesia in Children

Start date: May 2024
Phase: N/A
Study type: Interventional

Carbon Dioxide (CO2) is a by-product of metabolism and is removed from the body when we breathe out. High levels of CO2 can affect the nervous system and cause us to be sleepy or sedated. Research suggests that high levels of CO2 may benefit patients who are asleep under anesthesia, such as by reducing infection rates, nausea, or recovery from anesthesia . CO2 may also reduce pain signals or the medication required to keep patients asleep during anesthesia; this has not been researched in children. During general anesthesia, anesthesiologists keep patients asleep with anesthetic gases or by giving medications into a vein. These drugs can depress breathing; therefore, an anesthesiologist will control breathing (ventilation) with an artificial airway such as an endotracheal tube. Changes in ventilation can alter the amount of CO2 removed from the body. The anesthesiologist may also monitor a patient's level of consciousness using a 'Depth of Anesthesia Monitor' such as the Bispectral Index (BIS), which analyzes a patient's brain activity and generates a number to tell the anesthesiologist how asleep they are. The investigator's study will test if different levels of CO2 during intravenous anesthesia are linked with different levels of sedation or sleepiness in children, as measured by BIS. If so, this could reduce the amount of anesthetic medication the child receives. Other benefits may be decreased medication costs, fewer side effects, and a positive environmental impact by using less disposable anesthesia equipment.

NCT ID: NCT06297720 Not yet recruiting - Anesthesia Clinical Trials

Early Oral Hydration After Thoracoscopic Surgery

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn about the safety and feasibility of early oral hydration in patients receiving video-assisted thoracoscopic surgery after general anesthesia. The main questions aims to answer: - the safety and feasibility of oral hydration supplementation in the recovery room following general anesthesia. - the degree of improvement in sore throat and dry mouth after oral hydration. - the side effects and risks of oral hydration supplementation, such as the incidence of postoperative nausea and vomiting. - the impact of oral hydration supplementation in the recovery room following general anesthesia on hemodynamics. - patient satisfaction with oral hydration supplementation in the recovery room following general anesthesia. Participants will receive a series of oral hydration from swab moistening, and ice cube hydration to water hydration in the recovery room. Researchers will compare with the standard, no-hydration group to see if it is safe and feasible to hydrate patients in the recovery room.