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Anesthesia; Adverse Effect clinical trials

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NCT ID: NCT06382961 Completed - Delirium in Old Age Clinical Trials

Postoperative Dexmedetomidine in Prevention of Postoperative Delirium

Start date: November 11, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn how postoperative infusion of dexmedetomidine would influence postoperative delirium in elderly patients undergoing lung surgery. The main questions it aims to answer are : 1. Does postoperative dexmedetomidine reduce the incidence of delirium after lung surgery? 2. Does postoperative dexmedetomidine introduce other medical problems? Researchers will compare dexmedetomidine and sufentanil to see if dexmedetomidine works to reduce delirium. Participants will undergo routine postoperative care: 1. Patient-controlled self anesthesia with sufentanil only or combination of sufentanil and dexmedetomidine 2. Postoperative visit twice a day for at least seven days

NCT ID: NCT05868642 Completed - Anesthesia, Local Clinical Trials

Impatto Emodinamico Dell'Anestesia Subaracnoidea Titrata Versus Tecnica Single-shot Nei Pazienti Sottoposti ad Artroprotesi d'Anca. RCT

NINO
Start date: June 25, 2018
Phase: N/A
Study type: Interventional

Studying the hemodynamic effects of titrated subarachnoid anesthesia versus conventional single-shot subarachnoid anesthesia

NCT ID: NCT05584904 Completed - Clinical trials for Anesthesia; Adverse Effect

A Single Dry EEG Electrode Allows to Estimate of the Level of Anesthesia During Colonoscopy Sedation.

Start date: January 13, 2023
Phase:
Study type: Observational

We asked to a staff of digestive endoscopy and of the operating room to interpret the EEG traces obtained from a single dry electrode device to estimate the level of anesthesia during colonoscopy. They are required to produce a rank value (1 to 3) proportional to the anesthesia level. The rank values of anesthesia evaluated through the EEG traces will be correlated to the typically used "bispectral index" values simultaneously acquired. The expected efficacy of a low-cost single dry-electrode EEG would allow the monitoring of the level of anesthesia during non operating room procedures such as colonoscopy.

NCT ID: NCT05383417 Completed - Dysphagia Clinical Trials

No Post Intubation Laryngeal Symptoms

No-PILS
Start date: November 8, 2022
Phase: N/A
Study type: Interventional

The purpose of the study is to test a novel endotracheal tube support device that reduces pressure of the tube on the voice box for prevention of post intubation laryngeal symptoms including sore throat, change in voice and trouble swallowing.

NCT ID: NCT05368415 Completed - Clinical trials for Cesarean Section Complications

Comparison Between Three Norepinephrine Bolus Doses for Management of Post-spinal Hypotension During Ceaserian Section for Patients With Preeclampsia

Start date: May 15, 2022
Phase: Phase 4
Study type: Interventional

Maternal hypotension after subarachnoid block is a frequent and deleterious complication during lower segment caesarean section (LSCS). Prophylaxis against hypotension using vasopressors had become a standard recommendation. In mothers with preeclampsia, post-spinal hypotension is less frequent compared to healthy mothers; thus, the latest guidelines do not recommend using vasopressors in preeclampsia patients unless there is a hypotensive episode . The incidence of post-spinal hypotension in mother with preeclampsia is nearly 25%. The commonly used vasopressors during CS are ephedrine, phenylephrine, and recently norepinephrine. The use of ephedrine is usually accompanied with maternal tachycardia and foetal acidosis. Phenylephrine (PE) had been the first line for prevention and management of maternal hypotension; however, its use in mothers with preeclampsia had not been adequately investigated. Thus, the best vasopressor for management of hypotension in mothers with preeclampsia is unknown. Norepinephrine (NE) is an alpha adrenergic agonist with weak beta adrenergic agonistic activity; thus, it does not cause significant cardiac depression as phenylephrine does. NE was introduced for use during CS with promising results when used as infusion and as boluses in healthy mothers . The use of NE boluses in management of hypotension in preeclamptic mothers was not adequately investigated. A dose 4 mcg NE was recently evaluated in preeclamptic mothers. In this study, we will compare 3 NE bolus doses (3 mcg, 4 mcg, and 5 mcg) in management of maternal hypotension after spinal block during CS in preeclamptic mothers.

NCT ID: NCT04685980 Completed - Clinical trials for Cesarean Section Complications

Factors Associated With Failed Spinal Anesthesia for Cesarean Delivery

Start date: December 25, 2020
Phase:
Study type: Observational

The aim of this study is to reveal the factor associated with failed spinal anaesthesia in cesarean delivery. We conduct the retrospective case-control study to elucidate the involving factors.

NCT ID: NCT04679818 Completed - Clinical trials for Anesthesia; Adverse Effect

Postoperative Consequences of Intraoperative NOL Titration

Start date: December 30, 2020
Phase: Phase 3
Study type: Interventional

To demonstrate that intraoperative NOL-guided titration of fentanyl improves initial recovery characteristics.

NCT ID: NCT04634981 Completed - Clinical trials for Anesthesia; Adverse Effect

Does the Mode of Anesthesia Affect the Feto-maternal Outcome in Category-1 Caesarean Section

Start date: August 12, 2020
Phase:
Study type: Observational

Spinal anesthesia (SA) has become the standard technique in elective cesarean section (CS) as it results in less maternal and neonatal morbidity than general anesthesia (GA) (Grade-A recommendation, NICE). For women requiring emergency CS, rapid sequence general anesthesia (RSGA) is commonly used because this technique is faster to perform than SA. Though several randomized trials have compared the maternal and fetal outcome between these two anesthetic techniques, the studies with respect to category 1 CS (emergent conditions that hold immediate threat to life of the woman or fetus) are limited.

NCT ID: NCT04455776 Completed - Clinical trials for Sedation Complication

Safety Evaluation of Propofol Sedation for Magnetic Resonance Imaging in Pediatric Patients

Start date: July 3, 2020
Phase:
Study type: Observational

Propofol is often used for sedation in children undergoing magnetic resonance imaging. The investigators will perform a chart review of 4 month of activity (about 100 cases) and review the incidence and severity of adverse events of this sedation technique.

NCT ID: NCT04284644 Completed - Anesthesia Clinical Trials

Co-induction Technique Compared to Standard Inhalational and Intravenous Induction Techniques

Start date: May 1, 2016
Phase: N/A
Study type: Interventional

Co-induction technique refers to the use of a combination of medications to reach the desired therapeutic target. In the present study, the investigators examined the safety of a novel co-induction approach that relied on a simple timing and dosing alterations to the classical approaches of inhalational sevoflurane and propofol induction. The significance of this study is to find a reliable safe alternative method of induction that can provide optimal parameters,when compared to the classical methods of induction.