Risk Factor for Readmission and Death of Lower Respiratory Infections in Older Adults

Anemia Clinical Trial

Official title:

Anemia is a Risk Factor for Readmission and Death of Lower Respiratory Infections in Older Adults

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05355324
• Other study ID #: YuHe_1987
• Status: Completed
• Start date: March 1, 2016
• Est. completion date: December 31, 2021

Study information

• Verified date: April 2022
• Source: Beijing Tongren Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Lower respiratory tract infection(LRTI) is a prevalent disease that threatens the health of older people worldwide. Anemia is also a common disorder in the elderly, and its prevalence increases significantly with age. Most factors that contribute to the development of anemia are improvable. Therefore, we investigated whether anemia was a risk factor for LRTI-caused readmission and death in the elderly occurring within 1 year of discharge from the hospital.

Description:

Objectives: To investigate the effect of anemia on readmission and deaths in the older adults following lower respiratory tract infection (LRTI)-caused hospitalization.

Design: A retrospective cohort study. Setting and Participants: Older patients (age: ≥ 80 years) hospitalized at the Department of Geriatrics, from March 2016 to December 2019 to undergo treatment for LRTIs were included.

Methods: The patients were divided into two groups (anemia and non-anemia) based on the level of hemoglobin. They were kept under observation till the occurrence of mortality event or 1 year after discharge. The primary follow-up outcome was LRTI-caused readmission and/or death.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 215
• Est. completion date: December 31, 2021
• Est. primary completion date: December 31, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 80 Years to 100 Years

Eligibility

Inclusion Criteria:

• Age = 80 years

• lower respiratory tract infection

Exclusion Criteria:

• Died at the time of first admission

• Active malignancy

• Tuberculosis

• Anemia caused by gastrointestinal bleeding of unknown origin

• Achalasia of the cardia

• Could not be followed up after discharge

• Data were missing

Related Conditions & MeSH terms

• Anemia
• Communicable Diseases
• Death
• Infections
• Lower Respiratory Infection
• Readmission
• Respiratory Tract Infections

Intervention

Other:
• no intervention
no intervention

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Beijing Tongren Hospital

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Number of Patients with Readmission and/ or Death Caused by Lower Respiratory Tract Infection(LRTI) within One Year of Discharge	Number of Patients with Readmission Caused by LRTI within One Year of Discharge. Number of Patients with Death Caused by LRTI within One Year of Discharge.	March 2016 to 27 December 2019