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Anemia clinical trials

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NCT ID: NCT03480178 Not yet recruiting - ESRD Clinical Trials

Renal Anemia Refractory to Erythropoietin

Start date: January 2019
Phase:
Study type: Observational

This study evaluates the renal anemia refractory to Epo . in hemodialysis patients. all of participants will receive Epo. and identify various factors contributing to etiology of renal anemia in Epo- resistant patients.

NCT ID: NCT03295058 Not yet recruiting - Clinical trials for Severe Aplastic Anemia

Peripheral Blood Allogenic Stem Cell Transplantation Using Non-anti Thymocyte Globulin Regimens in Severe Aplastic Anemia Patients

Start date: January 1, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

Aplastic anemia is a syndrome of bone marrow failure characterized by peripheral pancytopenia and marrow hypoplasia.The theoretical basis for marrow failure includes primary defects in or damage to the stem cell or the marrow microenvironment

NCT ID: NCT03145896 Not yet recruiting - IBD Clinical Trials

The Correlation Between Anemia of Chronic Diseases, Hepcidin and Vitamin D in IBD Patients

Start date: June 1, 2017
Phase: N/A
Study type: Interventional

Crohn's disease (CD) and ulcerative colitis (UC) are chronic gastrointestinal diseases characterized by relapsing and remitting inflammation of the intestines Anemia may often complicate the course of inflammatory bowel disease (IBD). The cause of anemia in IBD is multifactorial In the chronically ill patients, it has been described that the mechanism underlying anemia involves hepcidin.A potential mechanism underlying anemia during an chronic disease is suggested by recent data demonstrating a hepcidin lowering effect of vitamin D

NCT ID: NCT03019900 Not yet recruiting - Anemia Clinical Trials

Survey of Blood Transfusion Practices in Critically Ill Patients at High Altitude

Start date: February 2017
Phase: N/A
Study type: Observational

The purpose of this study is to describe current practice on red blood cell transfusion in critically ill patients of intensive care units located in high altitude areas

NCT ID: NCT03005847 Not yet recruiting - Anemia Clinical Trials

The Effect of Fermented Papaya Preparation on Patients With Chronic Kidney Disease Under Dialysis Receiving Intravenous Iron

Start date: March 2017
Phase: N/A
Study type: Interventional

Fermented papaya preparation has been reported to bind and neutralize reactive oxygen species as well as iron. Patients undergoing hemodialysis are generally on iron overload status due to their inability to use iron storage adequately. The aim of this study is to evaluate the effect of FPP on the iron status of these patients.

NCT ID: NCT02969811 Not yet recruiting - Clinical trials for Anaemia, Myocardial Ischaemia, Fractured Neck of Femur

Cardiac Injury and Anaemia Following Surgery for Fractured Neck of Femur: An Observational Study Study Protocol: Cardiac Injury and Anaemia Following Surgery for Fractured Neck of Femur

Start date: December 2016
Phase: N/A
Study type: Observational

Blood transfusion is an expensive and finite resource and optimum transfusion threshold in surgical patients is yet to be defined. Patients commonly receive blood transfusions to reduce the risk of myocardial ischaemia or improve perfusion of other organs (e.g. the kidneys), but this treatment may have important adverse effects including postoperative infection. Patients undergoing surgery for fractured neck of femur are often elderly, with co-morbidities and a high risk of postoperative complications, including MI and AKI. We propose to conduct a study with the following aims: 1. To describe the incidence of anaemia and transfusion in patients undergoing surgery for fractured neck of femur. 2. To use clinical and biochemical data to measure the incidence of perioperative cardiac and kidney injury in this group. 3. To evaluate highly sensitive serum troponin and urinary MALDI-MS as possible endpoints in a future prospective randomised trial of perioperative transfusion.

NCT ID: NCT02939794 Not yet recruiting - Anemia Clinical Trials

The Effect of Ferric Carboxymaltose on Hemoglobin and Blood Transfusion in Cardiac Surgery

Start date: November 2016
Phase: Phase 4
Study type: Interventional

Anemia after cardiac surgery is a vast phenomena. More than 70% of the patients who under went surgery represented with hemoglobin less than 8 mg/dl (the cutoff for blood transfusion) and more than 80% of the patients receives at least one unit of red blood cell transfusion. There were number of attempts to prevent the postoperative anemia by giving erythropoietin, Iron per os and intra venus iron. non of the above have shown increase in Hemoglobin after the cardiac surgery.

NCT ID: NCT02857530 Not yet recruiting - Anemia, Aplastic Clinical Trials

Efficacy and Safety of Thrombopoietin In Patients With Severe and Very Severe Aplastic Anemia

Start date: August 2016
Phase: Phase 2
Study type: Interventional

Efficacy and Safety of Recombinant human thrombopoietin in patients with severe aplastic anemia and very severe aplastic anemia, a randomized, double-blind, placebo-controlled, II phase, multi-center clinical research.

NCT ID: NCT02838992 Not yet recruiting - Aplastic Anemia Clinical Trials

ATG Combined With Cyclophosphamide And Cord Blood Transfusion in Treating Patients With Severe Aplastic Anemia

Start date: February 2017
Phase: Phase 4
Study type: Interventional

To assess whether ATG Combined With Cyclophosphamide and cord blood infusion can accelerate hematopoietic reconstruction in severe aplastic anemia patients and improve clinical curative effect and safety

NCT ID: NCT02833493 Not yet recruiting - Aplastic Anemia Clinical Trials

Study of MRI Monitoring in Patients With Aplastic Anemia and Low or Int-1 Risk of MDS Complicated With Iron Overload

Start date: September 2016
Phase: N/A
Study type: Observational

The investigators aim to give an overview of Iron overload(IOL) of patients with AA and low and int-1 risk MDS and their sequelae under different chelation treatment. And the investigators also aim to evaluate the relationship of LIC and T2*/R2*.