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Anemia clinical trials

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NCT ID: NCT06220461 Not yet recruiting - Extreme Prematurity Clinical Trials

Folic Acid Supplementation to Reduce Anemia in Extremely Preterm Infants

FASCINATE
Start date: June 1, 2024
Phase: N/A
Study type: Interventional

Anemia of Prematurity (AOP) is very common in extremely preterm infants and often leads to blood transfusions. Folic acid, essential for growth and DNA synthesis, is deficient in premature infants. Despite the adoption of folic acid supplementation, evidence supporting its effectiveness in preventing AOP remains scarce. Recommendations for folic acid intake exceed what's naturally found in breast milk, particularly for extremely low birthweight infants. Practices regarding folic acid supplementation vary widely, prompting the need for research. The FACINATE trial aims to determine if additional folic acid supplementation improves hemoglobin levels and reduces late blood transfusions in extremely preterm infants, a question not addressed in current literature.

NCT ID: NCT06219395 Not yet recruiting - Clinical trials for Iron Deficiency Anemia

Capsule Endoscopy in Iron Deficiency Anaemia

WCE-IDA
Start date: March 1, 2024
Phase:
Study type: Observational

This project aim to investigate whether wireless capsule endoscopy(WCE) has a similar diagnostic yield as conventional endoscopy in detecting the cause of iron deficiency anemia (IDA)

NCT ID: NCT06218953 Recruiting - Anemia Clinical Trials

The Impact of Preoperative Anemia on Postoperative Anemia and Related Nutrient Abnormalities After Bariatric Surgery

Start date: September 1, 2017
Phase:
Study type: Observational [Patient Registry]

This study aims to assess the impact of preoperative anemia status on anemia and related nutrient abnormalities 1 year after bariatric surgery.

NCT ID: NCT06213402 Recruiting - Sickle Cell Disease Clinical Trials

RADeep Multicenter European Epidemiological Platform for Patients Diagnosed With Rare Anemia Disorders (RADs)

RADeep
Start date: November 30, 2021
Phase:
Study type: Observational [Patient Registry]

Rare Anaemia Disorders (RADs) is a group of rare diseases characterized for presenting anaemia as the main clinical manifestation. Different medical entities classified as RADs by ORPHA classification are most of them chronic life threating disorders with many unmet needs for their proper clinical management creating an impact on European health systems. RADs present diagnostic challenges and their appropriate management requires from specialised multidisciplinary teams in Centers of expertise. Although there are some examples of well-established national registries on RADs in EU, the lack of recommendations for Rare disease registries implementation and the lack of standards for interoperability has led to the fragmentation or unavailability of data on prevalence, survival, main clinical manifestations or treatments in most of the European countries.

NCT ID: NCT06212154 Recruiting - Clinical trials for Autoimmune Hemolytic Anemia

CAR-T for Autoimmune Hemolytic Anemia Patients Who Have Failed Three or More Lines of Therapy

Start date: January 20, 2024
Phase: Phase 1
Study type: Interventional

To Evaluate the Safety and Efficacy of ThisCART19A for Relapsed/Refractory Autoimmune Hemolytic Anemia Patients After Receiving Three or More Lines of Therapy

NCT ID: NCT06210295 Not yet recruiting - Clinical trials for Refractory Anemia in Systemic Lupus Erythematosis

Anemia in Systemic Lupus Erythematosus Specially Refractory Type

Start date: March 9, 2024
Phase:
Study type: Observational

Systemic lupus erythroematosis (SLE) is a systemic autoimmune disease with multisystemic involvement. The condition has several phenotypes, with varying clinical presentations from mild mucocutaneous manifestations to multiorgan and severe central nervous system involvement. Several immunopathogenic pathways play a role in the development of SLE. Despite recent advances in technology and understanding of the pathological basis and risk factors for SLE, the exact pathogenesis is still not well known. Diagnosis of SLE can be challenging, and while several classification criteria have been posed, their utility in the clinical setting is still a matter of debate. Management of SLE is dictated by organ system involvement. Despite several agents shown to be efficacious in treating SLE, the disease still poses significant morbidity and mortality risks in patients[1]. Haematological abnormalities are common in systemic lupus erythroematosis. Anemia is found in about 50% of patients.

NCT ID: NCT06199362 Active, not recruiting - Anemia Clinical Trials

Early Life Anemia and Children's Risk of Neurodevelopmental Disorders: National and Regional Register-based Studies

Start date: August 15, 2023
Phase:
Study type: Observational [Patient Registry]

The overall project aim is to study children's neurodevelopmental outcomes (including diagnoses of autism, ADHD, and intellectual disability) following exposure to maternal anemia during pregnancy or anemia during the first year of life using national and regional Swedish health-data registers, and to assess children's neurodevelopmental outcomes over the range of maternal hemoglobin levels during pregnancy.

NCT ID: NCT06198790 Not yet recruiting - Anemia Clinical Trials

Postoperative Anemia After Bariatric Surgery

Start date: February 1, 2024
Phase:
Study type: Observational [Patient Registry]

To investigate the real incidence of short and long-term anemia after bariatric surgery, and explore the risk factors.

NCT ID: NCT06176430 Not yet recruiting - Cerebral Palsy Clinical Trials

Comparison of Twice Weekly Versus Daily Iron Therapy in Treating Anemia in Children With Cerebral Palsy

Start date: February 1, 2024
Phase: Phase 4
Study type: Interventional

a randomized clinical trial to compare the effect of twice weekly versus daily iron therapy in treating anemia in children with cerebral palsy, to be conducted at Department of pediatric medicine children's hospital PIMS islamabad.

NCT ID: NCT06176105 Completed - Anemia Clinical Trials

Mortality After Transfusion of Ever-pregnant Donor Red Blood Cells

MATER
Start date: October 1, 2019
Phase:
Study type: Observational

The MATER study is an observational cohort study on first ever transfusion recipients in six hospitals in the Netherlands, with information collected on both donor and patient characteristics. We aim to further specify which combination of characteristics of both donors and patients determine the increased risk of mortality after blood transfusions.