Anemia, Iron Deficiency Clinical Trial
Official title:
Anemia of Inflammation and Deficiency Anemia in Critically Ill Patients; Biological Markers
Critical patients which requiring admission to intensive care (IT) are a special group of
patients. In these patients the prevalence of anemia reported in studies is 75%. This
prevalence is similar to that in the retrospective observational study conducted in our
intensive care unit(ICU). Of the 783 patients included in the study, 551 (73.37%) had anemia
on admission. Frequently anemia is present on discharge from ICU or hospital and may persist
for an average of 11 weeks. Some studies have reported the presence of anemia as far as 6
months after discharge. It is widely accepted that anemia has a negative impact on
rehabilitation and quality of life, but the treatment can not be exclusively based on blood
products due to the risks associated with transfusion. Alternative treatments such as
injectable iron or erythropoietin should be considered.
The Transfusion Management Initiative Group recently issued recommendations on perioperative
anemia. Similar recommendations for ICU have not yet been developed in Romania. The current
study has two main purposes. The first to adopt the perioperative anemia diagnostic algorithm
and adapt it to anemic patients on ICU; the second to identify patients with mixed anemia
(inflammatory and iron deficient anemia) who can benefit from treatment with iron.
n/a
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