PET Study of Acetylcholine Esterase Activity in Alzheimer's Disease

Status Completed

Clinical Trial Summary

The aim of this study is to understand regional variations in acetylcholine esterase activity in Alzheimer's disease. In this study the aim is to identify by PET the physiological values of the regional activity of acetylcholine esterase using the 11C PM4 tracer and to study by PET and 11C PM4 the brain activity of acetylcholine esterase in a group of patients with Alzheimer's disease, enrolled according to the inclusion and exclusion criteria. The PET data will be correlated with the clinical, neuropsychological and morphological data acquired by MRI and with the clinical-cognitive outcome.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Alzheimer Disease

Clinical Trial Details

NCT number	NCT06180252
Study type	Observational
Source	IRCCS San Raffaele
Contact
Status	Completed
Phase
Start date	May 12, 2004
Completion date	January 29, 2008

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