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Alopecia clinical trials

View clinical trials related to Alopecia.

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NCT ID: NCT06399783 Not yet recruiting - Alopecia Areata Clinical Trials

Topical Simvastatin Versus Topical Steroid in Treatment of Alopecia Areata

Start date: October 1, 2024
Phase: Phase 4
Study type: Interventional

Alopecia areata (AA) is an autoimmune disorder characterized by non-scarring hair loss of the scalp or any hair-bearing surface. Alopecia areata affects approximately 2% of the general population. AA has a significant influence on patients' quality of life and may induce psychological disorders. In AA, CD4+ and CD8+ T-cells violate the immune privilege of the anagen hair follicle, leading to loss of the growing hair shaft. A genome-wide association study demonstrated a genetic predisposition to AA . Additionally, environmental insults, such as viral infections, trauma, or psychosocial stress, have also been suspected to possibly contribute to the development of the disease . The clinical manifestations of AA vary from small well-defined patches of hair loss to the diffuse involvement of the scalp or the entire body. The majority of AA patients experience unpredictable relapsing and remitting episodes. In a number of patients, it can be persistent, especially when the hair loss is extensive.

NCT ID: NCT06393452 Not yet recruiting - Clinical trials for Androgenetic Alopecia

Safety, Pharmacokinetics and Efficacy of PP405 in Adults With AGA

Start date: June 2024
Phase: Phase 2
Study type: Interventional

The study is designed to validate safety results from the Phase 1 PP405-001 trial while also characterizing longer term safety and PK following 28 days of administration.

NCT ID: NCT06355856 Not yet recruiting - Alopecia Clinical Trials

Efficacy/ Safety of DNN.22.17.036 in Male Patients With Pattern Hair Loss

CAPELLI
Start date: April 2024
Phase: Phase 4
Study type: Interventional

Evaluation of the efficacy and safety of DNN.22.17.036 versus 10573048700 in the treatment of male pattern hair loss.

NCT ID: NCT06326359 Not yet recruiting - Androgenic Alopecia Clinical Trials

Autologous Stromal Vascular Fraction in Treatment of Male Androgenic Alopecia

Start date: March 2024
Phase: N/A
Study type: Interventional

Evaluation of Safety and efficacy of autologous stromal vascular fraction derived from denovo versus platelet rich plasma enhanced donner site in treatment of male androgenic alopecia

NCT ID: NCT06324695 Not yet recruiting - Psoriasis Clinical Trials

Development and EValuation of an Online Intervention to Reduce Self-Stigma in People With Visible Chronic Skin disEases

DEVISE
Start date: March 2024
Phase: N/A
Study type: Interventional

This project aims to develop and evaluate an online intervention to prevent and/or reduce self-stigma in German patients with visible chronic skin diseases. Evaluation of the intervention with regard to effectiveness and feasibility will follow an open-label randomized controlled design with 550 patients in total. The results of the program are expected to provide new insights and markedly extended knowledge on the mechanisms of self-stigma in chronic skin conditions. The new online intervention can be used in routine care, aiming for better patient care in practice and, ultimately decreased extent of self-stigma, increased quality of life of patients, and decreased rates of depression, anxiety, and suicide ideation.

NCT ID: NCT06292533 Not yet recruiting - Alopecia Clinical Trials

Effectiveness of Ultrapulse for the Treatment of Androgenic Alopecia Among Malaysian: A Quasi-experimental Study

Start date: March 2024
Phase: N/A
Study type: Interventional

The goal of this study is to to evaluate the effectiveness of Ultrapulse for the treatment of androgenic alopecia among Malaysian. The main questions it aims to answer are: - the efficacy of Ultrapulse in treatment of androgenic alopecia among Malaysian - the safety and adverse effect of Ultrapulse treatment. - the quality of life of androgenic alopecia among Malaysian.

NCT ID: NCT06279221 Not yet recruiting - Alopecia Areata Clinical Trials

Litfulo Capsules Special Investigation

Start date: April 30, 2024
Phase:
Study type: Observational

The objective of this Study is to confirm the safety during the long-term use of this drug and the effectiveness during the use of this drug under the actual use in the patients treated with this drug.

NCT ID: NCT06240351 Not yet recruiting - Clinical trials for Frontal Fibrosing Alopecia

A Study to Evaluate the Safety and Efficacy of Baricitinib in the Treatment of Frontal Fibrosing Alopecia (FFA)

Start date: June 1, 2024
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to evaluate the safety and efficacy of Baricitinib in the treatment of frontal fibrosing alopecia (FFA).

NCT ID: NCT06215469 Not yet recruiting - Breast Cancer Clinical Trials

Portable Scalp Cooling System (PSCS) to Prevent Hair Loss for Breast Cancer Patients (Cooler Heads)

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

The purpose of this post-market, prospective study is to assess the ability of AMMA to prevent hair loss in women receiving chemotherapy (CT) for early-stage breast cancer.

NCT ID: NCT06149936 Not yet recruiting - Alopecia Areata Clinical Trials

Excimer Light(308) Therapy for Resistant Alopecia Areata

Start date: December 1, 2023
Phase:
Study type: Observational [Patient Registry]

This study aimed to evaluate the efficacy and safety of the 308-nm excimer lamp in resistant AA treated with topical minoxidil .