Enhancing Prospective Thinking in Early Recovery (BEAM)

Alcohol Use Disorder Clinical Trial

— BEAM  

Official title:

Enhancing Prospective Thinking in Early Recovery

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06283472
• Other study ID #: 1805574553; Aims 14-16
• Secondary ID: 2P60AA007611-403
• Status: Not yet recruiting
• Phase: N/A
• Start date: June 1, 2024
• Est. completion date: February 1, 2027

Study information

• Verified date: February 2024
• Source: Indiana University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The goal of this clinical trial is to test the prosocial effects of personally-relevant, high-intensity episodic future-thinking (EFT) cues in alcohol use disorder persons and related brain mechanisms. The main question[s] this trial aims to answer are: - Will high-intensity EFT cues will produce greater delayed reward preference than low-intensity cues? - Will high-intensity EFT cues effect greater treatment-seeking interest? - Will high-intensity EFT cues elicit greater response in regions for prospective thinking during delay discounting (vs. low-intensity) - Will nucleus accumbens-precuneus resting connectivity correlate with behavioral SS? - Will the novel behavioral SS decision-making task activate the nucleus accumbens? Researchers will compare the experimental (high-intensity group) and control (low-intensity) groups to see if there are differences in the results for the questions outlined above.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 150
• Est. completion date: February 1, 2027
• Est. primary completion date: December 1, 2026
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 60 Years

Eligibility

Inclusion Criteria:

• Individuals who meet current heavy drinking (=2 heavy drinking days/month OR =7 drinks/week for biological females, and =14 drinks/week if biological male [NIAAA definition] and/or AUDIT scores =8)
• English comprehension

Exclusion Criteria:

• Unstable medical disorders
• Outside the age range of 18-60
• Smell/taste disorders
• Unstable psychiatric conditions

Related Conditions & MeSH terms

• Alcohol Drinking
• Alcohol Use Disorder
• Alcoholism

Intervention

Behavioral:
• High-Intensity Cue
Participants in the high-intensity group will receive high-intensity image cues that represent self-reported events they did on the previous day and self-reported events they look forward to in the future.
• Low-Intensity Cue
Participants in the low-intensity group will receive low-intensity image cues that represent self-reported events they did on the previous day and self-reported events they look forward to in the future.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Indiana University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Increase Prospective Thinking	High-intensity episodic future-thinking image cues will change prospective thinking.	Study Day Visit (Day 1)
Primary	Delayed Rewards	High-intensity episodic future-thinking image cues will change preference for delayed rewards, which will be measured using a behavioral delayed discounting task.	Study Day Visit (Day 1)