Alcohol Dependence Clinical Trial
Official title:
Novel Pharmacotherapy for Dual Dependence
The purpose of this study is to evaluate the effects of Topiramate and Cognitive Behavioral Therapy for the treatment of alcohol and cocaine dependence.
Our objective is to understand the basic mechanisms that underpin substance dependence, and
to develop efficacious treatments for individuals with comorbid cocaine and alcohol
dependence.
Participants in this study will be randomly assigned to receive either 300 mg per day of
topiramate or placebo. In addition, participants will receive weekly cognitive behavioral
therapy for 12 weeks.Follow-up visits will occur at 2 weeks and 1,2,, and 3 months following
completion of treatment.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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