Alcohol Abuse Clinical Trial
In adolescents, mental health problems are frequently associated with substance misuse, even
considered a risk factor for alcohol abuse and dependence. This dual diagnosis tends to
complicate the patient's treatment and prognosis by increasing, among others, substance use
problems, reckless behaviours, relationships and school problems and suicidal thoughts. It
is therefore critical to invest time and effort into developing an efficient approach to
prevent and reduce substance use problems and offer these children a more global and optimal
treatment.
A brief personality-targeted intervention was developed with students of Canadian and
English high schools based on four personality factors known to be implicated in the
vulnerability to adolescent alcohol misuse (Impulsivity, Anxiety Sensitivity, Negative
Thinking and Sensation Seeking) (Conrod et al., 2006,2008, O'Leary-Barrett 2010).
By helping the adolescents to develop better adaptive behaviours, this cognitive-behavioural
intervention proved to reduce binge drinking, quantity and frequency of use and substance
use problems (Conrod et al., 2006,2011).
The purpose of this study is to assess the impact of this intervention if combined to a
regular treatment in a youth psychiatric population.
60 patients aged 14-17 years of a Child and Adolescent psychiatric department will be
screened for personality risk with self-report assessments including the Substance Use Risk
Profile Scale. Participants will be randomly assigned to a personality matched
cognitive-behavioural intervention or a no-intervention control.
The main outcome measures of this study are alcohol and illicit drug outcomes. Secondary
measures include mental health symptoms.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Factorial Assignment, Masking: Open Label, Primary Purpose: Prevention
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05246202 -
Personalized Feedback Intervention for Latinx Drinkers With Anxiety
|
N/A | |
| Completed |
NCT03165942 -
Neuroendocrine Response to Oral Alcohol Administration
|
Phase 1 | |
| Recruiting |
NCT05343039 -
Technology Enhanced Adolescent Mental Health (TEAM)
|
N/A | |
| Active, not recruiting |
NCT04070521 -
EEG Monitoring in the Emergency Department
|
||
| Completed |
NCT03169244 -
Buproprion for Binge Drinking
|
Phase 2 | |
| Completed |
NCT05036499 -
PFI for Pain-Related Anxiety Among Hazardous Drinkers With Chronic Pain
|
N/A | |
| Recruiting |
NCT04368416 -
Anxiety/Depression, Sleep and Alcohol in Elderly Anxiety/Depression, Sleep Disturbances and Alcohol Use Disorder in Elderly With Cognitive Complaints
|
||
| Not yet recruiting |
NCT04557631 -
Evaluation of the Threshold for the Interpretation of the Results of a Method for the Blood Determination of Phosphatidyléthanol
|
||
| Terminated |
NCT00890149 -
Ondansetron for the Treatment of Heavy Drinking Among Emerging Adults
|
Phase 2 | |
| Completed |
NCT02681406 -
Smartphone Based Continuing Care for Alcohol
|
N/A | |
| Completed |
NCT02179749 -
Mifepristone Treatment of Alcohol Use Disorder
|
Phase 2 | |
| Completed |
NCT02448134 -
A Community-Based Strategy for Preventing Underage Drinking
|
N/A | |
| Withdrawn |
NCT01796158 -
Pilot Test of Computerized MET to Reduce Adolescent Alcohol Use
|
N/A | |
| Withdrawn |
NCT01847300 -
cSBI-M for Young Military Personnel
|
N/A | |
| Withdrawn |
NCT01511679 -
Brain-imaging and Adolescent Neuroscience Consortium
|
N/A | |
| Completed |
NCT01553136 -
Varenicline Treatment of Alcohol Dependence in Smokers
|
Phase 2 | |
| Terminated |
NCT01408641 -
Topiramate for Alcohol Use in Posttraumatic Stress Disorder
|
N/A | |
| Withdrawn |
NCT01275391 -
cSBIRT to Reduce Teen Tobacco, Alcohol and Drug Use
|
Phase 1/Phase 2 | |
| Active, not recruiting |
NCT01539525 -
Screening to Augment Referral to Treatment- Project START
|
Phase 2 | |
| Completed |
NCT01207258 -
Brief Intervention for Problem Drinking and Partner Violence
|
Phase 2 |