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Mechanisms to Reduce Mental and Physical Fatigue Following Exercise Training in Older Adults — BCAA  

Aging Clinical Trial

Official title:
Mechanisms to Reduce Mental and Physical Fatigue Following Exercise Training in Older Adults

Clinical Trial Summary

Fatigue is a strong predictor of negative health outcomes in older adults. The research in this study will compared the effects of 8-weeks of branched chain amino acids (BCAAs: dietary supplements commonly taken to improve muscle growth and exercise performance) added to exercise on fatigue compared to exercise with a placebo (an inactive, harmless substance). BCAAs could have an impact on improving fatigue common in older adults, especially when exercising.

Clinical Trial Description

Thirty participants will be asked to participate in this research study. They will be randomized (like a flip of a coin) to exercise + a placebo or exercise + BCAAs for 8 weeks. We would like to examine the effects of the 8-week exercise + dietary supplement program on body composition (fat and muscle), physical activity habits, fatigue, and physical performance (such as walking and strength). We would also like to assess whether these outcomes are controlled by changes in markers (kynurenine metabolites) in the skeletal muscle and blood. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05484661
Study type Interventional
Source The University of Texas Health Science Center at San Antonio
Contact
Status Completed
Phase N/A
Start date December 22, 2022
Completion date November 30, 2023
View Details
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