Correlation of Muscle Ultrasound Measures (2D and 3D) With Biphotonic X-ray Absorptiometry in Oldest Old Patients.

Aging Clinical Trial

— DIASEM  

Official title:

Correlation of Muscle Ultrasound Measures (2D and 3D) With Biphotonic X-ray Absorptiometry in Oldest Old Patients.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04753450
• Other study ID #: RC20_0534
• Status: Completed
• Start date: March 9, 2021
• Est. completion date: October 19, 2022

Study information

• Verified date: November 2022
• Source: Nantes University Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The sarcopenia diagnosis is based on the muscle mass and on impaired physical performance. The emerging field of ultrasound assessment of muscle mass in older patients is based on 2d parameters with prediction equations for muscle mass. For the moment, validation of prediction equations in older adults with varying function and health is lacking. The study aims to evaluate correlation of muscle mass between 3D muscle mass measurement and DXA, in order to dispense with the prediction equation.

Description:

Older patients who agree to participate to the study will undergo 3D ultrasound muscle mass measurement, 2D panoramic mode muscle mass measurement and biphotonic X-ray absorptiometry assessment. Correlation analysis will be done with the different measurement.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 62
• Est. completion date: October 19, 2022
• Est. primary completion date: October 19, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 75 Years and older

Eligibility

Inclusion Criteria:

• Patients over 75 years old

• Osteoporosis diagnosis confirmed by Dual-energy X-ray Absorptiometry

Exclusion Criteria:

• Neurocognitive disorders preventing the expression of informed consent

• Patients who cannot undergo an examination in a static position

• Lack of a measurement site (muscle resection or amputation)

• Any state of dehydration or water inflation

• Patient with legal protection measure

Related Conditions & MeSH terms

• Aging
• Assessment, Self
• Muscle Atrophy
• Muscular Atrophy
• Ultrasound Therapy; Complications

Intervention

Other:
• No intervention
No intervention

Locations

Country	Name	City	State
France	CHU de Nantes	Nantes

Sponsors (1)

Lead Sponsor	Collaborator
Nantes University Hospital

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	3D Correlation between muscle volume measured by 3D ultrasound and standard method : DXA results	Correlation between muscle volume measured by 3D ultrasound and standard method : DXA results	1 week
Secondary	2D correlation between muscle volume measured by 2D ultrasound and standard method : DXA results	Correlation between muscle volume measured by 2D ultrasound and standard method : DXA results	1 week