Implementing a Physical and Cognitive Performance Assessment Cohort in the MURDOCK Study Community Registry and Biorepository

Aging Clinical Trial

— PPS  

Official title:

Implementing a Physical and Cognitive Performance Assessment Cohort in the MURDOCK Study Community Registry and Biorepository

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01720472
• Other study ID #: Pro00036608
• Status: Completed
• Start date: May 2012
• Est. completion date: August 28, 2018

Study information

• Verified date: January 2019
• Source: Duke University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

The purpose of this study is to use the MURDOCK Horizon 1.5 infrastructure (Duke Instutional Review Board Pro00011196) to specifically target and enroll 1,000 participants across age groups and other demographic categories in order to develop a diverse cohort with specific physical and cognitive performance data paired with biological samples.

Description:

The MURDOCK Study, proposes this Horizon 2 study to collect a brief physical and cognitive performance assessment from 1,000 MURDOCK Registry participants. Blood sample aliquots will also be obtained. These physical and cognitive performance data, paired with -omics data from plasma and serum sample analyses, offer promise in the discovery of biomarkers for functional decline. This research will provide an important basis for our understanding of the physical, lifestyle, and genetic factors which, over the lifespan, contribute to changes in physical and cognitive capabilities as we age.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 1000
• Est. completion date: August 28, 2018
• Est. primary completion date: August 28, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 30 Years and older

Eligibility

Inclusion Criteria:

• A resident of Cabarrus County and/or the city of Kannapolis (and surrounding regions) or certain portions of Rowan, Mecklenburg, or Stanly counties in North Carolina for 6 or more months of the year.

• Age 30 or older

Exclusion Criteria:

• Female that is currently pregnant

• Having had a heart attack, angina, congestive heart failure, or fluid in the lungs within the past 6 months

• Participant that requires consent by a legally authorized representative

• Participant that cannot walk 30ft without human assistance

Related Conditions & MeSH terms

• Aging
• Cognitive Functioning
• Fitness
• Physical Functioning

Intervention

Genetic:
• Biomarker studies

Locations

Country	Name	City	State
United States	Bethesda Health Center	Charlotte	North Carolina
United States	Carolinas Medical Center NorthEast Medical Arts Building	Concord	North Carolina
United States	McGill Family Medicine	Concord	North Carolina
United States	Ada Jenkins Center	Davidson	North Carolina
United States	Harrisburg Sleep Center	Harrisburg	North Carolina
United States	Lake Norman Community Health Clinic	Huntersville	North Carolina

Sponsors (1)

Lead Sponsor	Collaborator
Duke University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Implementing a Physical and Cognitive Performance Assessment Cohort in the MURDOCK Study Community Registry and Biorepository	Factors associated with physical function and physical activity and change in physical activity and function over two-year follow-up.	Upto 2 years or 24 months

External Links

•   MURDOCK Study Physical Performance Cohort