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NCT01720472 Clinical Trial

Implementing a Physical and Cognitive Performance Assessment Cohort in the MURDOCK Study Community Registry and Biorepository

Aging Clinical Trial

— PPS  

Official title:
Implementing a Physical and Cognitive Performance Assessment Cohort in the MURDOCK Study Community Registry and Biorepository

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01720472
Other study ID # Pro00036608
Secondary ID
Status Completed
Phase
First received
Last updated
Start date May 2012
Est. completion date August 28, 2018

Study information
Verified date January 2019
Source Duke University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational [Patient Registry]

Clinical Trial Summary

The purpose of this study is to use the MURDOCK Horizon 1.5 infrastructure (Duke Instutional Review Board Pro00011196) to specifically target and enroll 1,000 participants across age groups and other demographic categories in order to develop a diverse cohort with specific physical and cognitive performance data paired with biological samples.

Description:

The MURDOCK Study, proposes this Horizon 2 study to collect a brief physical and cognitive performance assessment from 1,000 MURDOCK Registry participants. Blood sample aliquots will also be obtained. These physical and cognitive performance data, paired with -omics data from plasma and serum sample analyses, offer promise in the discovery of biomarkers for functional decline. This research will provide an important basis for our understanding of the physical, lifestyle, and genetic factors which, over the lifespan, contribute to changes in physical and cognitive capabilities as we age.

Recruitment information / eligibility
Status Completed
Enrollment 1000
Est. completion date August 28, 2018
Est. primary completion date August 28, 2018
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 30 Years and older
Eligibility Inclusion Criteria:

- A resident of Cabarrus County and/or the city of Kannapolis (and surrounding regions) or certain portions of Rowan, Mecklenburg, or Stanly counties in North Carolina for 6 or more months of the year.

- Age 30 or older

Exclusion Criteria:

- Female that is currently pregnant

- Having had a heart attack, angina, congestive heart failure, or fluid in the lungs within the past 6 months

- Participant that requires consent by a legally authorized representative

- Participant that cannot walk 30ft without human assistance

Study Design

Related Conditions & MeSH terms

Intervention

Genetic:
• Biomarker studies

Locations
Country Name City State
United States Bethesda Health Center Charlotte North Carolina
United States Carolinas Medical Center NorthEast Medical Arts Building Concord North Carolina
United States McGill Family Medicine Concord North Carolina
United States Ada Jenkins Center Davidson North Carolina
United States Harrisburg Sleep Center Harrisburg North Carolina
United States Lake Norman Community Health Clinic Huntersville North Carolina

Sponsors (1)
Lead Sponsor Collaborator
Duke University

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Implementing a Physical and Cognitive Performance Assessment Cohort in the MURDOCK Study Community Registry and Biorepository Factors associated with physical function and physical activity and change in physical activity and function over two-year follow-up. Upto 2 years or 24 months
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