Aging Clinical Trial
Official title:
Study of the Evolution of the Expression of the LAMP-2 Protein During the Advance as Well as Variations and Allelic Mutations in the Main Genes Involved in the Occurrence of Age-related Myelodysplastic Syndromes
Recruitment on the RAV pole in consultation or day hospital. Competitive recruitment of subjects > 60 years of age respecting a male/female ratio = 1.
| Status | Not yet recruiting |
| Enrollment | 100 |
| Est. completion date | May 1, 2026 |
| Est. primary completion date | May 2, 2024 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 60 Years to 99 Years |
| Eligibility | Inclusion Criteria: - Men and women over 60 years of age. Exclusion Criteria: - Inability to Understand Consent, - Non-Security Beneficiaries - social, subjects protected by law, subjects deprived of liberty, - history of breast cancer, - brain tumor, - melanoma, - colon cancer, - lung cancer, - prostate cancer, - lymphoma, - myeloma, - syndrome myelodysplastic/myeloproliferative, - leukemia, - history of radiation therapy. |
| Country | Name | City | State |
|---|---|---|---|
| France | Chu de Nice | Nice |
| Lead Sponsor | Collaborator |
|---|---|
| Centre Hospitalier Universitaire de Nice |
France,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Expression level of LAMP2 (protein and isoform A and B mRNA) | dosage | day 0 | |
| Secondary | Presence of mutation in the "Oncomin Myeloid Reasearch Assay" gene panel targeting approximately 40 Different genes | dosage | day 0 |
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