Acute Stroke Clinical Trial
Official title:
New Acute Treatment for Stroke - The Effect of Remote PERconditioning
This study is a blinded randomized study. Randomization for treatment/not treatment with
remote perconditioning takes place during transportation to the hospital. This is because
the investigators' hypothesis states that remote perconditioning is neuro-protective and the
effect is proportionally larger with early treatment. As the size of the effect is unknown,
the investigators will use multiple magnetic resonance imaging (MRI) scans to determine the
size of a potential neuro-protective effect.
The aims of this study are:
1. To describe method of remote perconditioning in clinical practice regarding
feasibility. Pros and cons and potential limitations.
2. To estimate the size of the effect of remote perconditioning in combination with
recombinant tissue plasminogen activator (rtPa) treatment within four and a half hours
of onset of symptoms.
Final inclusion and informed consent takes place after first MRI in patients eligible for
rtPA.
Follow-up MRI after 24h and 1 month. Clinical outcome at 3 months.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Investigator, Outcomes Assessor), Primary Purpose: Treatment
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