Clinical Trials Logo
  1. Home
  2. Acute Pain Due to Trauma
  3. NCT04133623

Ibuprofen Versus Ketorolac by Mouth in the Treatment of Acute Pain From Osteoarticular Trauma — IbuKet  

Acute Pain Due to Trauma Clinical Trial

Official title:
Ibuprofen Versus Ketorolac by Mouth in the Treatment of Acute Pain From Osteoarticular Trauma: a Randomized Double-blind Controlled Study.

Clinical Trial Summary

Pain is the leading cause of access to the paediatric emergency department (ED) and present in up to 78% of cases. Acute osteoarticular traumatic pain is often treated inadequately, and there is little data about the best treatment for children. The ibuprofen and ketorolac are respectively the most used and one of the most powerful NSAIDs. In literature, there is no direct comparison between those two medications. The objective of the study depends on the level of pain: - in severe traumatic acute pain (>=7 points): to evaluate if ketorolac is superior to ibuprofen in the treatment of pain (n=130 children, 65 allocated to ketorolac and 65 to ibuprofen) - in moderate traumatic acute pain (<7 points): to evaluate if ibuprofen is not inferior to ketorolac in the treatment of pain (n=120 children, 60 allocated to ketorolac and 60 to ibuprofen)

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04133623
Study type Interventional
Source IRCCS Burlo Garofolo
Contact
Status Completed
Phase Phase 3
Start date November 19, 2019
Completion date September 30, 2021
View Details
See also
  Status Clinical Trial Phase
Completed NCT03247179 - The Mobile PTSD Coach App in Acute Injury Survivors N/A
Completed NCT05229965 - Paracetamol Vs Caffeine Vs Codeine in the Management of Post Traumatic Pain in Emergencies Phase 3
Completed NCT05630222 - Evaluation of Effect of Intravenous Morphine vs Intravenous Ibuprofen and Acetaminophen vs Intravenous Ibuprofen Phase 3
Recruiting NCT06351137 - Timecost of Intranasal Versus Intravenous Analgesia in Traumatic Pain N/A
Completed NCT03222518 - NSAIDs Versus Paracetamol Versus Paracetamol + NSAIDs in Traumatic Pain Management Phase 3
Completed NCT03256903 - Methoxyflurane vs Standard Analgesic Treatment for Trauma Pain in Spanish Emergency Units Phase 3
Completed NCT03080350 - Sublingual Versus Endovenous Fentanyl for the Prehospital Analgesia in Patients With Limb Trauma on the Slope Phase 4
Recruiting NCT06051227 - Fentanyl OR Esketamine for Traumatic PAIN (FORE-PAIN) Trial Phase 3
Completed NCT04914988 - Continuous Fascia Iliaca Compartment Block in Geriatric Hip Fracture
Recruiting NCT03421275 - Intranasal Esketamine and Fentanyl for Pain in Minor Trauma Phase 4
Completed NCT03080324 - Sublingual Versus Endovenous Fentanyl for Pain Treatment in Trauma Patients in the Emergency Room Phase 4
Completed NCT01420159 - Efficacy and Safety of Methoxyflurane (Penthrox) for the Treatment of Acute Pain in Minor Trauma Phase 3
Completed NCT03597945 - Magnesium-sulfate as Adjuvant in Prehospital Femoral Nerve Block for Patient With Diaphysial Femoral Fracture. N/A