Acute Pain Due to Trauma Clinical Trial
Official title:
Open Randomized Clinical Trial to Compare Pain Relief Between Methoxyflurane and Standard of Care for Treating Patients With Trauma Pain in Spanish Emergency Units.
Clinical trial to compare pain relief between methoxyflurane and any analgesic treatment used in usual clinical practice, in patients with trauma and associated pain, treated in Spanish emergency units.
Open, randomized clinical trial to compare emergency pain relief between methoxyflurane and
standard of care in patients with trauma and associated pain, treated in Spanish emergency
units.
Methoxyflurane is a fluorinated ethyl methyl ether, with the chemical name
2:2-dichloro-1:1-difluoroethyl methyl ether. It belongs to the fluorinated hydrocarbon group
of volatile anaesthetics. It is inhaled as a vapour at low (sub-anaesthetic) concentrations
to achieve an analgesic effect for the management of pain.
In Europe countries, where methoxyflurane is already marketed, it is indicated for emergency
relief of moderate to severe pain in conscious adult patients with trauma and associated
pain.
On the other hand, current clinical practice includes a variety of analgesic agents, with the
choice of which to employ based on consideration of the risk-benefit factors of each class of
drug, as well as the type of pain, its severity, and the risk of adverse effects.
The main objective of this study is to assess Methoxyflurane's significant advantage in terms
of anaglesic effectiveness, as it is known as a rapidly acting, non-narcotic analgesic for
the treatment of emergency pain.
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