Acute Coronary Syndromes Clinical Trial
Official title:
Does Optical Coherence Tomography Optimise Results of Stenting: The DOCTORS Study
Optical Coherence Tomography (OCT) is a recent imaging modality that yields cross-sectional
images with a resolution 10 times greater than that of intravascular ultrasound (IVUS). OCT
uses a near-infra-red light source to obtain images of the interior walls of the coronary
arteries and is increasingly used to evaluate vulnerable atherosclerotic plaques and assess
placement and response to stenting. - To date, no study has evaluated whether optical
coherence tomography (OCT) contributes to optimizing percutaneous coronary intervention (PCI)
and stenting.
The DOCTORS study is a randomized, open label study to evaluate whether OCT-guided
angioplasty would provide useful clinical information beyond that obtained by angiography,
and whether this information would subsequently modify physician behavior and treatment
choices. In particular, we will evaluate the impact of changes in procedural strategy
resulting from the use of OCT on the value of fractional flow reserve (FFR) obtained after
angioplasty and stent implantation of a lesion responsible for non-ST segment elevation acute
coronary syndromes.
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