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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT01403467
Other study ID # 02-52-28
Secondary ID MURA2009/1239
Status Completed
Phase Phase 4
First received July 25, 2011
Last updated July 26, 2011
Start date April 2009
Est. completion date January 2011

Study information

Verified date December 2010
Source Ramathibodi Hospital
Contact n/a
Is FDA regulated No
Health authority Thailand:Mahidol University
Study type Interventional

Clinical Trial Summary

This current study aimed to demonstrate the effectiveness of the addition of CPAP to the current conventional therapy in terms of airway obstruction improvement in acute asthma patients.


Description:

Continuous positive airway pressure (CPAP) is widely used in providing ventilator support. However, its role in an acute asthmatic attack is uncertain. The purpose of this study was to compare the efficacy of CPAP when used in addition to conventional therapy with conventional therapy alone in the management of acute asthma exacerbation.


Recruitment information / eligibility

Status Completed
Enrollment 86
Est. completion date January 2011
Est. primary completion date January 2010
Accepts healthy volunteers No
Gender Both
Age group 19 Years to 75 Years
Eligibility Inclusion Criteria:

- aged over 18 years

- known asthmatic patients visiting ED with acute exacerbation

- had given their written informed consent.

Exclusion Criteria:

- smoking history

- chronic obstructive pulmonary disease

- required intubation

- instability of hemodynamic or arrhythmia

- unable to perform PEFR

- facial abnormality

- pulmonary infiltration

- pregnancy.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms


Intervention

Device:
Continuous positive airway pressure
CPAP 8 cmH2O

Locations

Country Name City State
Thailand Ramathibodi Hospital Bangkok

Sponsors (1)

Lead Sponsor Collaborator
Ramathibodi Hospital

Country where clinical trial is conducted

Thailand, 

Outcome

Type Measure Description Time frame Safety issue
Primary an improvement in PEFR, as % predicted 75 mins No
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