Achalasia Clinical Trial
Spastic esophageal motility disorders induced significant symptoms including dysphagia, retrosternal pain and regurgitation. Per oral endoscopic myotomy (P.O.E.M.) is a novel approach to perform myotomy through the esophagus with long submucosal tunnel. This study aimed to investigate the feasibility and safety of P.O.E.M. and translate the techniques from animal study to clinical practice in human.
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Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label
Status | Clinical Trial | Phase | |
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Completed |
NCT01399476 -
Endoscopic Myotomy of the Lower Esophageal Sphincter for Achalasia
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N/A | |
Recruiting |
NCT05326113 -
The Effect of Physiotherapy on Post POEM Reflux
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N/A | |
Recruiting |
NCT06044155 -
redoPOEM : Failure of a First POEM
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Recruiting |
NCT02989883 -
Clinical Outcomes of Peroral Endoscopic Myotomy
|
N/A | |
Terminated |
NCT02606578 -
Achalasia Patient Reported Outcomes
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Recruiting |
NCT01793922 -
POEM Trial: Multi-center Study Comparing Endoscopic Pneumodilation and Per Oral Endoscopic Myotomy (POEM)
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N/A | |
Recruiting |
NCT01302288 -
Endolumenal Partial Myotomy for the Treatment of Esophageal Achalasia
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Phase 2 | |
Terminated |
NCT03875365 -
Institutional Outcome Data From Per-oral Plication of the Esophagus
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Enrolling by invitation |
NCT02770859 -
Per-Oral Endoscopic Myotomy (POEM) for the Treatment of Achalasia, Database Repository
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Recruiting |
NCT05905016 -
Prospective Evaluation of the Clinical Utility of Peroral Endoscopic Myotomy for Gastrointestinal Motility Disorders
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Completed |
NCT01692106 -
A Clinical Study of Per Oral Endoscopic Myotomy (POEM) in Patients Suffering From Achalasia
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N/A | |
Completed |
NCT01405469 -
Endoscopic Peroral Myotomy for Treatment of Achalasia
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N/A | |
Completed |
NCT01402518 -
Per-Oral Endoscopic Myotomy
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Not yet recruiting |
NCT00790465 -
Efficacy of Dark Chocolate in Achalasia Patients
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Phase 1/Phase 2 | |
Recruiting |
NCT01799967 -
Minimally Invasive Surgery of the Gastro-esophageal Junction
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Terminated |
NCT00604942 -
vMII for Measurement of Oesophageal Bolus Transport and Reflux
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N/A | |
Recruiting |
NCT06405412 -
Effects of Malnutrition on Respiratory and Renal Functions in Patients Undergoing Peroral Endoscopic Myotomy (POEM)
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N/A | |
Not yet recruiting |
NCT06042127 -
POEM-F for Achalasia International Study
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N/A | |
Completed |
NCT04752670 -
ConMed Beamer Study
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Completed |
NCT02314741 -
Peroral Endoscopic Myotomy (POEM) for Esophageal Motility
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N/A |