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redoPOEM : Failure of a First POEM — redoPOEM  

Achalasia Clinical Trial

Official title:
Efficacy and Safety After Failure of a First POEM

Clinical Trial Summary

observational study, measurement of efficacy in the cohort.

Clinical Trial Description

Achalasia is a motor disorder of the esophagus with a prevalence of 1/10000. Multiple treatments have been proposed, including endoscopic dilation, botulinum toxin injection and surgery using the Heller myotomy technique. These techniques are moderately effective and/or carry the risk of per- and post-procedural complications. POEM has been available since 2008, with 80-90% efficacy and 90% safety, and no serious complications have been reported. In the event of failure of a first POEM, a second POEM, known as "redoPOEM", can be proposed. Several studies show efficacy of between 76% and 96% and a safety of between 80% and 86%, with only one serious adverse event reported, and no deaths. However, the studies carried out involved small numbers of patients, generally around 50, the vast majority in Asian countries. The aim of this study was therefore to evaluate the efficacy and safety of redoPOEM reported in patients from several expert centers in Europe. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06044155
Study type Observational
Source University Hospital, Bordeaux
Contact Arthur BERGER, MD
Phone +335 57 65 64 39
Email arthur.berger@chu-bordeaux.fr
Status Recruiting
Phase
Start date October 3, 2023
Completion date January 2024
View Details
See also
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