Pr-conceptional Progesterone for Unexplained Recurrent Miscarriage

Status Completed

Clinical Trial Summary

In women with unexplained recurrent miscarriages, progesterone (400 mg pessaries, twice daily), started soon as possible at luteal phase and after a positive pregnancy test and continued to 28 weeks of gestation, compared to placebo, ).

Clinical Trial Description

Progesterone improves secondary outcomes such as gestation at delivery, on-going pregnancy at 12 weeks, survival at 28 days of neonatal life.

. Progesterone, compared to placebo, does not incur substantial adverse effects to the mother or the neonate.

Explore differential or subgroup effects of progesterone in prognostic subgroups.

. Perform an economic evaluation for cost-effectiveness. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

Abortion, Habitual

Clinical Trial Details

NCT number	NCT01670929
Study type	Interventional
Source	Woman's Health University Hospital, Egypt
Contact
Status	Completed
Phase	Phase 4
Start date	September 2012
Completion date	November 2015

View Details

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