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Use of Fish Oil to Reduce Inflammation During Endovascular Abdominal Aortic Repair — Omega-EVAR  

Abdominal Aortic Aneurysm Clinical Trial

Official title:
Omega EVAR: Use of Fish Oil to Reduce Inflammation During Endovascular Abdominal Aortic Repair.

Clinical Trial Summary

The purpose of this study is to determine if high-dose PUFA supplementation in patients undergoing EVAR for infra-renal AAA reduces the peri-operative inflammation.

Clinical Trial Description

In this 2:1 double-blind, randomized, placebo controlled trial, subjects will be given an active drug of n-3 polyunsaturated fatty acids (PUFAs) or a placebo soybean oil for about two weeks prior to an endovascular abdominal aortic repair (EVAR) and subsequently six months after the procedure. An EVAR is known to produce a systemic inflammatory response with an increased risk of prolonged hospitalization and complicated post-operative recovery with cardiac events, renal and pulmonary dysfunction, and multiple organ failure. The study proposed here has the potential to provide valuable insight on the role of nutritional intervention to improve outcomes related to surgical revascularization. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03208920
Study type Interventional
Source University of California, San Francisco
Contact
Status Completed
Phase N/A
Start date December 2016
Completion date August 28, 2018
View Details
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