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Zinc Deficiency clinical trials

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NCT ID: NCT02951715 Completed - Zinc Deficiency Clinical Trials

Improvement of Tinnitus After Oral Zinc on Patients With Noise-induced Hearing Loss

Start date: December 2013
Phase: N/A
Study type: Interventional

Twenty patients with tinnitus and a typical noise-induced hearing loss (NIHL) audiogram were included. Each subject underwent an otoscopic examination, distortion product otoacoustic emissions, tinnitus-match testing, Tinnitus Handicap Inventory (THI) and serum zinc level analyses. After 2 months of treatment with zinc, all tests were repeated.

NCT ID: NCT02760095 Completed - Clinical trials for Vitamin A Deficiency

Effects of EED on Zn Absorption and Retention in Children From a Standard Dose

ZEED1
Start date: November 2015
Phase:
Study type: Observational

The overall objective is to determine the impact of EED on zinc absorption and homeostasis, and its impact on the absorptive capacity of vitamin A absorption of young children (18-24 months of age) in an austere setting with high rates of diarrhea, stunting, and micro-nutrient deficiencies.

NCT ID: NCT02758444 Completed - Zinc Deficiency Clinical Trials

Effects of EED on Zn Absorption and Retention in Children From a MNP

ZEED2
Start date: November 2015
Phase: N/A
Study type: Interventional

The overall objective is to determine the impact of EED on total daily zinc absorption of young Bangladeshi children (18-24 months of age) in an austere setting with high rates of diarrhea, stunting, and micro-nutrient deficiencies..

NCT ID: NCT02648893 Active, not recruiting - Iron Deficiency Clinical Trials

Effect Of Multiple Biofortified Food Crops On Micronutrient Status And Immune Function Among Indian Infants and Their Mothers

MBFC
Start date: February 28, 2019
Phase: N/A
Study type: Interventional

In this study, meals based on multiple food crops (containing either biofortified or commercially-available food crops) will be fed to young children in Madanapalle, Andhra Pradesh, India over a period of nine months to measure growth, cognitive changes, and immune function in comparison to children receiving non-biofortified crops. Mothers of the participating children will also be included in the study.

NCT ID: NCT02337569 Completed - Zinc Deficiency Clinical Trials

A Randomized, Double-Blind, Placebo Controlled Study of NPC-02 in Patients With Zinc Deficiency

Start date: January 2015
Phase: Phase 3
Study type: Interventional

The objective of this study is to evaluate efficacy and safety of NPC-02 in patients with Zinc Deficiency.

NCT ID: NCT02321865 Completed - Zinc Deficiency Clinical Trials

Dose Adjustment Study of NPC-02 in Patients With Zinc Deficiency

Start date: January 21, 2015
Phase: Phase 3
Study type: Interventional

The objective of this study is to check the dose control method of NPC-02 and the holding effect for the target serum zinc concentration in patients with zinc deficiency.

NCT ID: NCT02319499 Completed - Iron Deficiency Clinical Trials

Zinc, Iron, Vitamin A and Psychosocial Care for Child Growth and Development

Start date: August 1998
Phase: Phase 3
Study type: Interventional

Many Indonesian infants are already iron deficient before they reach the age of six months, which also determines the high prevalence of anemia among under-five children. Iron deficiency ultimately leads to anemia, and there is clear evidence that iron deficiency anemia during early childhood has a marked negative effect on child development and cognitive function (Lozoff et al.1991; Idjradinata & Pollitt, 1993). This negative impact on childhood development is one of the main reasons why iron deficiency during infancy should be prevented or treated. Since diets low in iron is usually also low in zinc, zinc deficiency --which has negative consequence on growth-- is common in iron deficiency area. In Southeast Asia, the condition is exacerbated by the rich phytate content in the complementary foods which inhibits the absorption of iron as well as zinc (Gibson, 1994). Thus, combining both iron and zinc, hence, is expected to decrease both iron and zinc deficiencies and hence improve growth and development of the children. Recently, there has been an emerging view which looks at the two-way relationship between nutrition, health, and psychosocial well-being. This concept is supported by studies on "positive deviance", a term used to refer to children who grow and develop well in impoverished environments where most children are victims of malnutrition and chronic illness (Zeitlin et al., 1990). The mechanism which helps to explain how psychosocial factors, such as the affect between mother and child, are associated with adequate growth and development: 'Psychological stress has a negative effect on the use of nutrients whereas psychological well-being stimulates the secretion of growth-promoting hormones. Pleasantly stimulating interactions can enhance the child's tendency to exercise its developing organ systems and hence to utilize nutrients for growth and development'. Understanding how the psychosocial environment can promote or inhibit the benefit of supplementation intervention is necessary in order to have a better way of setting about providing supplements. In fact, many supplementation programs do not incorporate complementary program elements that would help to improve the health and psychosocial development of children at the same time that they improve nutritional status' (Myers, 1995). Looking from this perspective, not only will supplementation benefit the psychosocial development but also the psychosocial environment can promote the benefit of the supplementation on the nutritional status and developmental outcomes of infants. The purpose of the study is to investigate whether multi-micronutrient supplementations (zinc+iron, zinc+iron+vit.A) have positive effect on infants' growth and developmental outcomes, and whether the effect is modified by psychosocial care.

NCT ID: NCT02292303 Completed - Zinc Deficiency Clinical Trials

Clinical Trial to Determine the Bioavailability of Three Different Zinc Preparations

Start date: October 2014
Phase: N/A
Study type: Interventional

The main objective of this clinical is to get information on pharmacokinetics of zinc-enriched yeast.The bioavailability of the yeast enriched with zinc will be compared to two selected zinc salts used in food supplements that are zinc oxide and zinc gluconate.

NCT ID: NCT02241330 Completed - Zinc Deficiency Clinical Trials

Efficacy of Zn Biofortified Wheat in Improving Zn Status in Indian School Children With Low Zn Status

Start date: October 2014
Phase: N/A
Study type: Interventional

The objective of this research is to test the efficacy of Zn biofortified wheat in increasing Zn status in Indian school children aged 6-12 y via a 6 month randomized controlled trial.

NCT ID: NCT02233764 Completed - Iron Deficiency Clinical Trials

Effect of Iron/Zinc-Biofortified Pearl Millet on Growth and Immunity in Children Aged 12-18 Months in India

Start date: May 8, 2017
Phase: N/A
Study type: Interventional

In this study, iron- and zinc-biofortified pearl millet will be fed to young children in Mumbai, Maharashtra, India over a period of nine months to measure growth and immune function in comparison to children receiving non-biofortified pearl millet.