Skin Barrier Biophysical Properties and Clinical Appearance After Moisturizer in Dry Skin

Xerosis Cutis Clinical Trial

Official title: Evaluating Skin Barrier Biophysical Properties and Clinical Appearance After Moisturizer Use in Patients With Dry Skin

Status Completed

Clinical Trial Summary

The purpose of the study is to compare the changes in the appearance of dry skin after the use various moisturizers: white petrolatum ointment, coconut oil, jojoba oil, and almond oil in patients with dry skin.

Clinical Trial Description

The goal of this study is to compare how the appearance of dry skin changes before and after the use of following moisturizers: white petrolatum, coconut oil, jojoba oil and almond oil). Up to 40 subjects from Banner-University Medical Center/University of Arizona dermatology clinics and University of California, Davis dermatology clinics (up to 20 subjects per site) who have dry skin will be enrolled in this study and randomized to receive the four moisturizers on four locations on their forearms.There will be a total of 3 study sessions: baseline, and approximately 1 and 2 weeks for follow up assessment. At each visit, dry skin severity will be evaluated by a trained observer using a validated Dry Skin Score, skin barrier biophysical properties (transepidermal water loss and hydration) will be measured, and digital photos of the test sites will be taken for image analysis. ;

Related Conditions & MeSH terms

• Dry Skin; Eczema
• Xerosis
• Xerosis Cutis

• NCT number: NCT03093597
• Study type: Interventional
• Source: University of Arizona
• Status: Completed
• Phase: N/A
• Start date: March 27, 2017
• Completion date: December 12, 2017