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X-Linked Protoporphyria clinical trials

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NCT ID: NCT05020184 Recruiting - Clinical trials for Erythropoietic Protoporphyria

Effect of Oral Cimetidine in the Protoporphyrias

Start date: June 14, 2022
Phase: Phase 2
Study type: Interventional

Erythropoietic protoporphyria (EPP) and X-linked protoporphyria (XLP) result from genetic defects of heme biosynthesis that cause life-long, painful cutaneous sensitivity to light. The objective of this study is to determine the efficacy and safety of oral cimetidine administration for treatment of the protoporphyrias. Efficacy will be based on protoporphyrin levels, photosensitivity, and quality of life questionnaires. Funding Source- FDA OOPD