X-linked Hypophosphatemia Clinical Trial
Individual patient expanded access requests may be considered for patients who have no other treatment options
Expanded access may be available outside of the US in countries prior to approval by the local regulatory agencies. For full details, please visit the links provided below. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02915705 -
Efficacy and Safety of Burosumab (KRN23) Versus Oral Phosphate and Active Vitamin D Treatment in Pediatric Patients With X Linked Hypophosphatemia (XLH)
|
Phase 3 | |
| Recruiting |
NCT03879915 -
Dental Implants in Patients With X-linked Hypophosphatemia
|
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| Active, not recruiting |
NCT03193476 -
Registry for Patients With X-Linked Hypophosphatemia
|
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| Completed |
NCT02526160 -
Study of KRN23 in Adults With X-linked Hypophosphatemia (XLH)
|
Phase 3 | |
| Completed |
NCT05181839 -
A Study to Describe the Lived Experience of XLH for Adolescents at End of Skeletal Growth
|
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| Completed |
NCT04146935 -
Examining the Effect of Burosumab on Muscle Function
|
Phase 4 | |
| Completed |
NCT02750618 -
Study of the Safety, Pharmacodynamics (PD) and Efficacy of KRN23 in Children From 1 to 4 Years Old With X-linked Hypophosphatemia (XLH)
|
Phase 2 | |
| Active, not recruiting |
NCT03745521 -
Study of Longitudinal Observation for Patient With X-linked Hypophosphatemic Rickets/Osteomalacia in Collaboration With Asian Partners
|
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| Completed |
NCT03920072 -
Study of the Anti-FGF23 Antibody, Burosumab, in Adults With XLH
|
Phase 3 | |
| Recruiting |
NCT03748966 -
Calcitriol Monotherapy for X-Linked Hypophosphatemia
|
Early Phase 1 | |
| Recruiting |
NCT04419363 -
Burosumab in Children and Adolescents With X-linked Hypophosphatemia
|
Phase 4 | |
| Completed |
NCT02163577 -
Study of KRN23 (Burosumab), a Recombinant Fully Human Monoclonal Antibody Against Fibroblast Growth Factor 23 (FGF23), in Pediatric Subjects With X-linked Hypophosphatemia (XLH)
|
Phase 2 | |
| Active, not recruiting |
NCT03651505 -
X-linked Hypophosphatemia Disease Monitoring Program
|
||
| Completed |
NCT06067932 -
Foot Disorders in X-linked Hypophosphatemia
|
||
| Completed |
NCT04695860 -
Anti-FGF23 (Burosumab) in Adult Patients With XLH
|
Phase 3 | |
| Completed |
NCT02312687 -
Long-Term Extension Study of KRN23 in Adult Subjects With X-Linked Hypophosphatemia (XLH)
|
Phase 2 | |
| Completed |
NCT03596554 -
X-linked Hypophosphatemia and FGF21
|
||
| Recruiting |
NCT03820518 -
Using Different Doses of Active Vitamin D Combined With Neutral Phosphate in Children With X-linked Hypophosphatemia
|
Phase 4 | |
| Completed |
NCT01571596 -
An Extension Study of KRN23 in Adults With X-Linked Hypophosphatemia
|
Phase 1/Phase 2 | |
| Completed |
NCT04273490 -
Characterising Pain, QoL, Body Composition, Arterial Stiffness, Muscles and Bones in Adult Persons With XLH and Healthy Controls
|