A Randomized Trial of Ostomy Closure Techniques

Status Completed

Clinical Trial Summary

Stoma closure has been associated with a high rate of surgical site infection (SSI). The rate for SSI following stoma closure has been noted to be 7-41%; a rate that is higher than expected for a clean-contaminated operative classification. The ideal stoma site closure technique is still debated in the current literature. The aim of this study was to compare the rate of SSI following two different stoma closure techniques, primary closure versus a skin approximating purse string closure, in a multi-center randomized controlled trial. The investigators hypothesize that purse string closure technique will have a lower rate of SSI than primary closure technique.

Clinical Trial Description

The investigators will randomize ileostomy takedown patients to either a primary closure or purse string closure technique intraoperatively. Surgeons at both the University of Minnesota and the CHUV hospital in Switzerland will participate in the this study. ;

Study Design

Related Conditions & MeSH terms

Wound Infection

Clinical Trial Details

NCT number	NCT01713452
Study type	Interventional
Source	University of Minnesota
Contact
Status	Completed
Phase	N/A
Start date	December 2008
Completion date	October 2012

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT02905955` - Vacuumtherapy After Venous Hybrid Procedures	Phase 4
Not yet recruiting	`NCT02868372` - Swabbing of Subcutaneous Tissues of Cesarean Section Wounds With Povidone Iodine	N/A
Enrolling by invitation	`NCT02559453` - Outcomes for 2 Operations Versus ≥ 3 Operations in Infected Wounds	N/A
Completed	`NCT02744144` - Wound Bacterial Microbiota and Their Antibiotic Resistance	N/A
Active, not recruiting	`NCT01939145` - Comparing Outcomes for Prontosan Versus Normal Saline for Negative Pressure Wound Therapy With Instillation	Phase 4
Completed	`NCT00998907` - PDS*Plus and Wound Infections After Laparotomy	N/A
Completed	`NCT01141335` - Polypropylene Mesh Versus Polytetrafluoroethylene (PTFE) Mesh in Inguinal Hernia Repair	Phase 4
Terminated	`NCT00654641` - Prevention of Wound Complications After Cesarean Delivery in Obese Women Utilizing Negative Pressure Wound Therapy	N/A
Completed	`NCT00576745` - A Comparison Of The 3M TM S Surgical Skin Closure System To The Standard Vicryl Suture Closure of Sternotomy Incisions During Cardiac Surgery	Phase 1
Completed	`NCT00402727` - Comparison of Sequential IV/PO Moxifloxacin With IV Piperacillin/Tazobactam Followed by PO Amoxicillin/Clavulanic Acid in Patients With a Complicated Skin and Skin Structure Infection	Phase 3
Recruiting	`NCT00150852` - Prevention of Gastrostomy-Related Wound Infection by Vancomycin in Carriers of Methicillin-Resistant Staphylococcus Aureus.	Phase 2
Not yet recruiting	`NCT03872544` - Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
Recruiting	`NCT04596124` - Effectiveness and Tolerability of Fitostimoline Plus Cream and Gauze vs Connettivina Bio Plus Cream and Gauze	N/A
Active, not recruiting	`NCT04584957` - Prophylactic Negative Pressure Wound Therapy (VAC) in Gynecologic Oncology (G.O.)	N/A
Recruiting	`NCT03960970` - Two-drug Antibiotic Prophylaxis in Scheduled Cesarean Deliveries	Phase 2
Enrolling by invitation	`NCT03880188` - Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
Completed	`NCT02018094` - The Amputation Surgical Site Infection Trial (ASSIT)	Phase 4
Terminated	`NCT03269968` - Use of Negative Pressure Wound Therapy in Morbidly Obese Women After Cesarean Delivery	N/A
Enrolling by invitation	`NCT02945761` - High Concentration of Sugar Solution Irrigation Promotes the Healing of Infected Wound	N/A
Not yet recruiting	`NCT02882360` - Kerlix for Pregnant Women With Elevated BMI to Prevent Wound Infection by 6 Weeks Post Partum	Phase 4