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Wound Healing clinical trials

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NCT ID: NCT04613336 Enrolling by invitation - Wound Healing Clinical Trials

Efficacy of Topical Heparin Spray on Donor Site Wound Healing Time Compared to Conventional Dressing Among Patients Undergoing Split Thickness Skin Grafting

Start date: September 30, 2020
Phase:
Study type: Observational

Wound is defined by the breach in dermis of the skin. It can be caused by road traffic accidents, tumor excision, chronic illness like diabetes, bed sores in bedridden patients, burns, insects' bites etc. Treatment goals for wound coverage includes earliest debridement, dressings, local antibiotics, limb elevation, fracture fixations and wound coverage. Skin graft functions both as occlusive dressing, as a skin replacement and as a stimulus for healing. Even though the usage of flaps to cover the wounds has been increased recently still skin grafting serves as an easiest and simplest way of covering the wound. However, skin grafting introduces another wound in addition to the existing wound, the donor site wound (DSW). A secondary donor-site wound (DSW) is formed after harvesting split thickness skin graft which adds up with the primary wound to increase the total size of the wounds for the healing process. This donor site wound cause itching, pain and cosmetic embarrassment. That is why the proper and timely healing of the donor site wound is of great importance. Basic management of DSWs includes conventional dressings that provides absorption of bleeding solely.

NCT ID: NCT04513886 Completed - Wound Healing Clinical Trials

Healing After Connective Tissue Graft Harvesting in the Palatal Area With and Without Suture

Start date: November 19, 2018
Phase: N/A
Study type: Interventional

This study evaluated the outcomes in the early healing of palatal wounds after harvesting a subepithelial connective tissue graft (SCTG) using the single incision technique with placement of a collagen haemostatic sponge (CHS) without suturing the palate. The primary outcome of this study was to evaluate the early wound healing index (EHI).

NCT ID: NCT04455490 Completed - Wound Healing Clinical Trials

Clinical Effect of Endoscopic Surgery for Delayed Wound Healing After Achilles Tendon Suture

Start date: March 18, 2020
Phase:
Study type: Observational

This study proposes endoscopic surgery for delayed wound healing after Achilles tendon suture which is a brand new treatment,and retrospectively analyzed the clinical data of 4 cases treated with this treatment. The analysis results of the clinical efficacy of the method can serve as a reference for clinical and surgical decision-making and prognosis assessment.

NCT ID: NCT04310280 Completed - Wound Healing Clinical Trials

Effects of Local Insulin on Varicose Ulcers for Wound Healing

Start date: June 1, 2019
Phase: Phase 3
Study type: Interventional

A randomized, split-plot, double-blind, placebo-controlled trial. The varicose ulcer is divided into two (side A and B). Half of the wound's surface is treated locally with insulin (Glargine) applied at an approx depth of 3-4 mm. Treatment with insulin is administered for 7 days. Biopsy specimens of the two sides are obtained on days 0 and 7. A thermographic photograph of the wound is taken at days 0 and 7. The number of blood vessels and fibroplasia is evaluated as the main outcome.

NCT ID: NCT04290260 Completed - Wound Healing Clinical Trials

Use of the Bra as Prevention of Sternal Wound Dehiscence in Cardiac Surgery

DEHISCENCIA
Start date: January 2015
Phase: N/A
Study type: Interventional

The aim of the study was to assess the efficacy of bra application as a prevention of dehiscence in women with median sternotomy.

NCT ID: NCT04234321 Recruiting - Wound Healing Clinical Trials

Clinical Study of Kangfuxin and Basic Fibroblast Growth Factor in Promoting the Healing of Donor Site

Start date: August 1, 2020
Phase: N/A
Study type: Interventional

The main objective of this study is to observe whether basic fibroblast growth factor and Kangfuxin Liquid can promote the wound healing in the donor area and further evaluate the healing quality.

NCT ID: NCT04198454 Enrolling by invitation - Wound Healing Clinical Trials

Compression and CO2 Laser for Leg Wounds

Start date: February 17, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the efficacy and safety of compression bandaging with fractional ablative carbon dioxide laser (FACL) compared to compression and standard dressings alone for healing of post-operative wounds of the leg. This is a randomized, SMART design, clinical trial. Approximately 80 participants will be randomized to initially receive compression bandages or standard wound dressings after surgery on the lower leg. After 4 weeks, the group assigned to compression bandages will be further randomized to either continue with the compression bandages only or continue with the compression bandages and also receive (FACL). The study is designed as an 6-month study. This study was a pilot study designed to determine feasibility of these procedure. Subjects currently living in the Chicago metropolitan area and meet inclusion/exclusion criteria will be considered for enrollment.

NCT ID: NCT04189302 Not yet recruiting - Wound Healing Clinical Trials

Comparative Evaluation of Two Surgical Blades

Start date: January 2020
Phase: N/A
Study type: Interventional

this study compares the ease of execution, wound healing and patient morbidity of 2 surgical blade designs.

NCT ID: NCT04088357 Completed - Wound Healing Clinical Trials

Efficacy of Topical TolaSure on Acute Induced Wounds in Healthy Participants

Start date: August 26, 2019
Phase: Phase 2
Study type: Interventional

TolaSure is a topical gel for the promotion of accelerated wound healing. This phase II study will primarily assess the efficacy of TolaSure when applied to skin wounds created by punch biopsy in healthy participants. Safety, cutaneous tolerability, wound pain control, and quality of healing will also be assessed. A total of 80 healthy volunteers, males and females ages 18 years or older, will be enrolled. Subjects will be monitored for safety and efficacy until wound closure (estimation about 8 weeks) following topical administration of TolaSure.

NCT ID: NCT04040933 Completed - Wound Healing Clinical Trials

A Study to Assess Wound Healing Efficacies of Different Adhesive Bandages

Start date: August 9, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the wound healing efficacy (time to complete healing) of different adhesive bandages.