White Spot Lesions Clinical Trial
Official title:
Clinical Evaluation of White Spot Lesions Treated by Surface Pre-reacted Glass Filler Coating Material and Composite Sealants in Comparison With Icon Resin Infiltration by Using Laser Fluorescence and Spectrophotometer
Verified date | September 2022 |
Source | Al-Azhar University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Dental caries is the primary cause of tooth loss and oral diseases. Dental decay is a continuous pathological process with loss of tooth minerals, demineralization, which involves the destruction of tooth structure from acids. The first sign of early active demineralization is white spot lesions (WSLs) on the tooth surface, meanwhile, subsurface active mineral decomposition.
Status | Completed |
Enrollment | 20 |
Est. completion date | December 3, 2021 |
Est. primary completion date | December 2, 2021 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 20 Years to 40 Years |
Eligibility | Inclusion Criteria: - Patients within 20-40 years of age. - Each patient has 4 or more WSLs. - Mild and moderate WSLs according to Gorelick's scale. - Good oral hygiene and willing patients who can attend the study visits. - a Symmetrical number of permanent teeth in each arch (mesial to second molars). Exclusion Criteria: - Active carious lesions. - Facial surface restorations. - Intrinsic and extrinsic stains. - Patients who have a significant medical history or if they smoke. - Criteria for discontinuation; Mortality and acquiring severe debilitating disease |
Country | Name | City | State |
---|---|---|---|
Egypt | Mohamed Wakwak | Cairo |
Lead Sponsor | Collaborator |
---|---|
Al-Azhar University |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Assessments of caries lesion state of WSLs: | Assessing of carious lesions state of WSLs, was performed by using Diagnodent pen to record the progression or regression of caries by time. The assessment of the WSLs demineralization condition took place before intervention (baseline) [T0], immediately after intervention [T1], 3 months later [T2] ,6 months later [T3] and 1 year later [T4]. | 1 year | |
Secondary | Assessment of color change of WSLs: | The difference in color of the WSLs were performed by Vita Easyshade V at the five distinct times: before intervention (baseline) [T0], immediately after intervention [T1], 3 months later [T2] ,6 months later [T3] and 1 year later [T4]. | 1 year |
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