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Clinical Trial Summary

To evaluate the effectiveness of ginger and rosemary herbals versus sodium fluoride in remineralization of incipient enamel caries.


Clinical Trial Description

Group 1 (intervention)

Ginger and rosemary gel application:

First the participant will be asked to brush his/her teeth thoroughly with 1450 ppm fluoride toothpaste (Colgate total healthy clean toothpaste). Then an application of a thin ribbon of this gel to the teeth using a brush. The medication will be left for at least 1 minute. The participant will be asked to spit out the medication after use and not to swallow it. Also the participant will be asked not to rinse his/her mouth, eat, or drink for at least 30 minutes after use to get the best results.

Group 2 (control group). Sodium fluoride varnish The fluoride varnish will be bifluorid 10 single use by voco (Germany). It Contains 5 % sodium fluoride (equal to 22,600 ppm fluoride).

A thin coat will be applied on the tooth surface by using a brush. 10-20 s are sufficient for the varnish to be absorbed and then dry with air. Participants will be informed that they should not brush their teeth for 12-24 hours after the application and not to eat, or drink for at least 30 minutes after use to get the best results. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03990935
Study type Interventional
Source Cairo University
Contact manaa
Phone 00201022484815
Email sara.mohamed.manaa@hotmail.com
Status Not yet recruiting
Phase N/A
Start date July 2019
Completion date June 2020

See also
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Completed NCT05562856 - Clinical Evaluation of White Spot Lesions Treated by S-PRG Material and Composite Sealants in Comparison With ICON N/A
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Completed NCT02341872 - Compare the Efficacy of the Remineralization Agents on the White Enamel Lesions N/A