White Spot Lesion Clinical Trial
Official title:
Comparison of Three Orthodontic Bonding Systems in White Spot Lesion Development: A Randomized Clinical Trial
The gaol of this randomized clinical trial was to compare the effect of self-etching primer bonding system and one step adhesive bonding system on the development of white spot lesions (WSLs) during fixed orthodontic therapy in comparison with the conventional 3 step bonding system. All participants will be bonded with similar fixed orthodontic appliances using each type of adhesives for the assigned group. WSLs will be monitored during the orthodontic treatment
Objectives: The objective of this clinical trial was to compare the effect of self-etching primer bonding system and one step adhesive bonding system on the development of WSLs during fixed orthodontic therapy in comparison with the conventional 3 step bonding system. Materials and Methods: Seventy five patients were randomly allocated into 3 groups (Group 1, conventional bonding system, n=25; Group 2, self-etch primer n=25; Group 3, primer mixed with the adhesive composite n=25). Quantitative light-induced fluorescence (QLF) was used to quantify WSL parameters. Images were captured and then analyzed before treatment; 2 months and 4 months after bond-up. Lesion area (Pixels), mean fluorescence loss (∆F) and the number of newly developed WSLs were compared within and between the 3 groups. The significance level was set at P ≤ 0.05. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05710874 -
A Prospective, Randomized, Clinical Study on the Effects of CPP-ACP-paste, Fluoride and a Combination on the Evolution of White Spot Lesions in Orthodontic Patients After Debonding.
|
N/A | |
| Completed |
NCT04107012 -
Evaluation of Enamel Demineralization During Clear Aligner Orthodontic Treatment
|
N/A | |
| Active, not recruiting |
NCT04342858 -
Prospective Randomized Controlled Trial for Prevention of Demineralization During Fixed Orthodontic Treatment
|
Phase 2 | |
| Recruiting |
NCT05989750 -
Air-polishing With Erythritol During Orthodontic Tretament
|
N/A | |
| Completed |
NCT06200129 -
İmportance of Scattered White Spots Detected in the Duodenum and Their Relationship wıth Zonulin
|
N/A | |
| Not yet recruiting |
NCT03976583 -
Remineralization Potential of Pearl Powder Compared to CPP-ACP on Enamel White Spot Lesions
|
Phase 2 | |
| Not yet recruiting |
NCT06051981 -
White Spot Lesions Treatment in Orthodontic
|
Phase 4 | |
| Not yet recruiting |
NCT04422860 -
Remineralization Efficacy of Gum Arabic Varnish.
|
Phase 2/Phase 3 | |
| Completed |
NCT04560478 -
Comparing Fluoride Varnish and Sealant to Prevent White Spots in Orthodontic Patients
|
N/A | |
| Completed |
NCT02027922 -
Clinical Effectiveness of Various Professionally Applied Fluoride Prophylaxes in Groups at High Risk
|
N/A | |
| Completed |
NCT04908293 -
Home Remineralization of White Spot Lesions With Two Different Toothpastes.
|
N/A | |
| Not yet recruiting |
NCT05868603 -
Effect of Different Remineralization Gels
|
N/A | |
| Not yet recruiting |
NCT06331442 -
The Effect of Photodynamic Therapy on Plaque in Orthodontic Patients
|
N/A | |
| Not yet recruiting |
NCT05306691 -
Remineralizing Efficacy of Giomer Varnish vs. Fluoride Varnish in Management of White Spot Lesions in Adult Patients
|
Early Phase 1 | |
| Active, not recruiting |
NCT06166849 -
Clinical Evaluation of an Experimental Remineralization Product
|
N/A | |
| Completed |
NCT05775250 -
Evaluation of Two Varnishes on the Improvement of White Spot Lesions in Children
|
N/A | |
| Not yet recruiting |
NCT06358066 -
The Remineralization of Early Enamel Caries in Permanent Teeth
|
Phase 1 | |
| Completed |
NCT03114475 -
Effect of CO2 Laser on Enamel White Spot Lesion Formation Around Orthodontic Brackets
|
N/A | |
| Active, not recruiting |
NCT06403371 -
The Effect of Fluoride Varnish on White Spot Lesion in Clear Aligner Orthodontic Patients
|
N/A | |
| Completed |
NCT05771077 -
Effect of Poly Amido Amine Dendrimer, Nano-hydroxyapatite
|
Phase 1 |